Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 17, Problem
Summary Introduction
To review:
The different types of noncovalent interactions that stabilize the structure of deoxyribose
Introduction:
The DNA stores the genetic information of theorganisms. This genetic information is stored in the form of a genetic code. The genetic code is written in the form of nitrogenous bases such as adenine, thymine, cytosine, and guanine. These bases are arranged on two antiparallel strands and linked to each other by hydrogen bonds. The DNA is a stable structure and its stability is maintained by several noncovalent bonds.
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When nitrogenous bases in single-stranded polynucleotides are incorporated into doublestranded molecules, base pair formation results in altered UV light absorption. This is called the _____________ effect
Enzymes isolated from bacteria that cut DNA at specificsequences are called ____________________.
A base change that has no discernible effect is called a____________________ mutation.
Chapter 17 Solutions
Biochemistry: The Molecular Basis of Life
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- Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA repreduction. are important biological a) Compare the process of protein synthesis between eukaryote mRNA and viral RNA b) With the aid of a diagram, draw an adapter molecule that recognizes the codons of mRNA and explain its functions in DNA translation.arrow_forwardFour basic properties of the genetic code are specificity, degenerate, almost universal, and _____________.arrow_forwardQuestion 49 The Sanger method of DNA sequencing follows the principle of complementarity just like in the replication process. A) True B) Falsearrow_forward
- Sequence changes in DNA are called ______________.arrow_forward(Thanks for the help if you can break down the steps and provide drawings(needed) during the answer since i am trying to see if i have solved this in the right way not copy :) Let's consider a guanine - cytosine base pair, as observed in B- DNA. How does the anticancer medication cisplatin binds to such a base pair, and how many base pairs generally attach to a single Pt? Make sure to draw the resulting coordinationarrow_forwardQUESTION NO. 1 Patients with the rare genetic disease xeroderma pigmentosum (XP) are very sensitive to light and are highly susceptible to skin cancers. The study of such patients has enhanced our knowledge of DNA repair because XP is caused by defective DNA repair nucleotide excision repair. (A variant, XP-V, is deficient in postreplication repair.) In nucleotide excision repair A. removal of the damaged bases occurs on only one strand of the DNA. B. only thymine dimers generated by UV light can be removed . C. the excision nuclease is an exonuclease. D. a single multifunctional enzyme carries out the repair process. E. only the damaged nucleotides are removed. QUESTION NO.2 Homologous recombination: A. occurs only between two segments from the same DNA molecule. B. requires that a specific DNA sequence be present. C. requires one of the duplexes undergoing recombination be nicked in both strands. D. involves a…arrow_forward
- The eukaryotic mRNA is protected from degradation by a 3′ _____________.arrow_forwardThe sequence of the complementary strand of 5' GTCTATAGAC 3' is_____________ Is there anything special about this sequence?arrow_forwardQuestion 1.)Draw the main chain structure of a parallel beta sheet that has 4 amino acids in one strand and 5 in the other. Show all of the backbone atoms.Write R1, R2, R3, etc, instead of drawing side chains with the following exception: draw one proline in its entiretywith its side chain. You can put it anywhere in your sheet – I will find it. Add in all hydrogen bonds that stabilize this sheet using dashed lines.arrow_forward
- Question 45 When TRNAS and rRNAs have bases that H-bonds with other bases far apart from each other, the RNA molecules assume its secondary and tertiary structure. A) True B) Falsearrow_forwardThese questions relates to DNA extraction, the choices are in the attached photos (i) Sanger sequencing originally used 4 lanes in gels. These lanes represented sequences of different lengths obtained by adding: (ii)Which of the following gels is the preferred choice for separation of DNA fragments?arrow_forwardIf Adenine was added where Guanine should have been added, this would be an example of a ___________________ mutation.arrow_forward
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