Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 17, Problem 17RQ
Summary Introduction
To review:
The structural features of anucleosome.
Introduction:
The nucleosome is a major eukaryotic complex of proteins and DNA (deoxyribonucleic acid), where DNA is wrapped around proteins. These proteins are called histones and are eight in number inside a nucleosome. Histones can regulate gene expression as they can undergo modifications, such as, acetylation and methylation.
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Question 1.
Enzymes, proteins and deoxyribonucleic acid (DNA)
macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA
repreduction.
are important biological
a) Compare the process of protein synthesis between eukaryote mRNA and viral RNA
b) With the aid of a diagram, draw an adapter molecule that recognizes the codons of mRNA
and explain its functions in DNA translation.
The eukaryotic mRNA is protected from degradation by a 3′ _____________.
Four basic properties of the genetic code are specificity, degenerate, almost universal, and _____________.
Chapter 17 Solutions
Biochemistry: The Molecular Basis of Life
Ch. 17 - Prob. 1QCh. 17 - Prob. 2QCh. 17 - Prob. 3QCh. 17 - Prob. 4QCh. 17 - Prob. 5QCh. 17 - Prob. 6QCh. 17 - Prob. 7QCh. 17 - Prob. 8QCh. 17 - Prob. 1RQCh. 17 - Prob. 2RQ
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- Question 45 When TRNAS and rRNAs have bases that H-bonds with other bases far apart from each other, the RNA molecules assume its secondary and tertiary structure. A) True B) Falsearrow_forwardExpressed sequences of DNA are called ________________.arrow_forwardNoncoding DNA sequences are called __________________.arrow_forward
- The genome’s functional gene products are either _____________ or _____________.arrow_forwardWhat is unusual about the answers for Questions 13k, 13l, 13m, and 13n? Because the multiple codons exist for most amino acids, the genetic code is said to be _____________.arrow_forwardThe purpose of mitosis in human cells is for the production of two diploid, _________________ cells.arrow_forward
- Question 2. Ribosomes are cellular structures that are composed of protein and RNA; this structure is responsible for catalyzing peptide bond formation between amino acids during a process known as translation. a) Many antibiotics that kill bacteria target translation. Why might this be an effective mechanism to kill bacteria? Why don't antibiotics also kill human (eukaryotic) ribosomes? b) The antibiotic Kasugamycin (KSG) destabilizes the P-site of the ribosome. Describe what parts of translation would be altered in the presence of this antibiotic. c) How does the following graph show the efficacy of translational knockdown with KSG? Met-Methionine C % of Met incorporation 100 80 60 40 20 0 + 0 2 4 6 8 KSG concentration (mg/ml) 10arrow_forwardTranslation Is Terminated by _______ ________ when a Stop Codon Is Reached.arrow_forwardQuestion 11 The triplet code allows many amino acids to be specified by more than one codon. Such a code is said to be A synonymous. B) degenerate. c unambigous D) universal.arrow_forward
- QUESTION NO. 1 Patients with the rare genetic disease xeroderma pigmentosum (XP) are very sensitive to light and are highly susceptible to skin cancers. The study of such patients has enhanced our knowledge of DNA repair because XP is caused by defective DNA repair nucleotide excision repair. (A variant, XP-V, is deficient in postreplication repair.) In nucleotide excision repair A. removal of the damaged bases occurs on only one strand of the DNA. B. only thymine dimers generated by UV light can be removed . C. the excision nuclease is an exonuclease. D. a single multifunctional enzyme carries out the repair process. E. only the damaged nucleotides are removed. QUESTION NO.2 Homologous recombination: A. occurs only between two segments from the same DNA molecule. B. requires that a specific DNA sequence be present. C. requires one of the duplexes undergoing recombination be nicked in both strands. D. involves a…arrow_forwardSuppose the codon sequence GUGCAAUUCGAGGCC has a single base pair mutation to GUGCAAUUCAAGGCC. If the old protein sequence was Val-Gln-Phe-Glu-Ala, what will be the new sequence encoded by the mutant gene? ____________________________.arrow_forward_____________ are the linear sequences of nucleotides in an organism’s genetic information.arrow_forward
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