To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin. Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

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Answer 1

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f What is the genotype of individual #13? A) ff B) FF C) Ff D) it is impossible to tell

Huntington diseases is a rare fatal, degenerative neurological disease in which individuals start to show symptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his father has Huntington disease.a. What is the probability that Joe will also develop the disease?b. Joe and his new wife have been eager to start a family. What is the probability that their first child will eventually develop the disease?

In man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?

Answer 2

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Answer 3

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Answer 4

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Answer 5

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 6

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Answer 7

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Answer 8

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 9

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 2 - Prob. 1P Ch. 2 - Prob. 2P Ch. 2 - Prob. 3P Ch. 2 - Prob. 4P Ch. 2 - Prob. 6P Ch. 2 - Prob. 7P Ch. 2 - Prob. 8P Ch. 2 - Prob. 9P Ch. 2 - Prob. 10P Ch. 2 - Prob. 11P

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin. Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Solution Summary: The author explains that the disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews.

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To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

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Chapter 2 Solutions