The probability of an affected child, if mother’s brother is affected. Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

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Answer 1

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?

Sickle cell anemia is an inherited red blood cell disorder in which there are not enough healthy red blood cells to carry oxygen throughout the body. The allele that causes sickle-cell anemia is autosomal recessive (s), and the dominant allele can be represented by S. How many offspring will be affected by the disorder if the mother is a carrier, and the father appears to be normal? (Include the gender) a. b. How many will become carriers? (include the gender) A- 三三三四四 II !!

Hemophilia is a disease caused by a gene found on the X chromosome. Therefore, it is referred to as a sex-linked disease. The recessive allele causes the disease. A man with hemophilia (xhy) marries a woman who is homozygous dominant (XHXH. A. Illustrate using a Punnett square the probability that their children will have the disease. B. Will any of their children have the disease? C. Predict the probabilities of their children having the disease.

Answer 2

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 3

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 4

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 5

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 6

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

Answer 7

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

Answer 8

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Answer 9

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Answer 10

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 11

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 2 - Prob. 1P Ch. 2 - Prob. 2P Ch. 2 - Prob. 3P Ch. 2 - Prob. 4P Ch. 2 - Prob. 6P Ch. 2 - Prob. 7P Ch. 2 - Prob. 8P Ch. 2 - Prob. 9P Ch. 2 - Prob. 10P Ch. 2 - Prob. 11P

Solution Summary: The author explains that Duchenne muscular dystrophy is acquired in an X-linked pattern because of the gene that can conduct a DMD-causing mutation on the Y chromosome.

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To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

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Chapter 2 Solutions

Solution Summary: The author explains that Duchenne muscular dystrophy is acquired in an X-linked pattern because of the gene that can conduct a DMD-causing mutation on the Y chromosome.

Concept explainers

Videos

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease. Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Want to see the full answer?

Chapter 2 Solutions

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.