Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 60P
Summary Introduction

To determine: The proportion of the sons that will have hypophosphatemia?

Introduction: Hypophosphatemia is an electrolyte disorder that includes there is a low level of phosphate in the blood. The signs involve dizziness, trouble in breathing, and lack of appetite. Also, complications constitute seizures, unconsciousness, rhabdomyolysis, and weakening of the bones.

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Julie (a female) has hemophilia. Based on this information, what can we say about the genotypes of her parents? If Julie has children with a normal male, what is the chance that her sons have hemophilia? What is the chance that her daughters have hemophilia? A condition called Alport syndrome is caused by a dominant X linked allele. Males who have this condition usually have kidney failure, while females who are heterozygous for the condition have blood in the urine, but usually do not have kidney failure. A male has this condition and has children with an unaffected female What percent of his daughters will show any of the symptoms? What percent of his sons will show any of the symptoms?
A form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal woman whose father had hemophilia marries a man who suffers with hemophilia.  What is the probability that their first daughter will have hemophilia?
an unaffected woman who is heterozygous for the x linked allele causing duchenne muscular dystrophy has children with a normal man. What is the probability that their first child is an unaffected daughter and their second child is an affected son?

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Introduction to Genetic Analysis

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