15. The following pedigree shows inheritance of Huntington's disease, a fatal geneticdisorder that causes neurodegeneration. Since signs and symptoms usually do notappear until adulthood, many who are carriers may not realize their risk of passing onthe disease-causing allele. The following pedigree represents a family in which somepeople are affected by Huntington's disease.Reeessive Triter btmnt beMecyplicaltyHinhetee a. Using just the information on this pedigree, is Huntington's disease caused by adominant allele or recessive alleles?b. What are the genotypes of the grandparents (I-1 and I-2)?c. What are the genotypes of the parents (II-6 and II-7)?d. If the parents above have another child, what is the chance that they will beaffected by the Hungtington's disease allele?e. What are the genotypes of the unaffected children (III-8, 9, 10)?f. What is the chance that the unaffected children above will pass on aHuntington's disease afele to their children?g. What is the genotype of the affected child (Il-11)?h. What is the charrce that the affected child above will pass on the Huntington'sdisease allele to a child?

Name: 15. The following pedigree shows inheritance of Huntington's disease,
Uploaded: 2024-03-20T06:43:04.000Z
Channel: Bartleby
Description: 15. The following pedigree shows inheritance of Huntington's disease, a fatal geneticdisorder that causes neurodegeneration. Since signs and symptoms usually do notappear until adulthood, many who are carriers may not realize their risk of passing o

Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional…

Science

Biology

The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing a the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington's disease. Reeesslve Trait pically రాంి m Domin

The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing a the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington's disease. Reeesslve Trait pically రాంి m Domin

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter3: Transmission Of Genes From Generation To Generation

Section: Chapter Questions

Problem 31QP

See similar textbooks

Similar questions

In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor recessive gene. If 2 normal parents had a daughter with the symptoms ofthis disease, and a normal son, what is the probability that he might be acarrier of the recessive gene?Express answer in fraction form.
In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor the recessive gene. Two normal parents had a daughter with thesymptoms of this disease, and a normal son who marries a normal womanwith an afflicted A test (salt concentration in perspiration of heterozygotes ishigher than normal) disclosed that both are indeed carriers of the gene. If thefirst child born to the mating in (b) was defective, what is the probability thatthe 2nd child would also be defective?Express answer in fraction form
A recently married man and woman discover that eachhad an uncle with alkaptonuria (black urine disease), arare disease caused by an autosomal recessive allele of asingle gene. They are about to have their first baby. Whatis the probability that their child will have alkaptonuria?
a. The ability to taste the chemical phenylthiocarbamideis an autosomal dominant phenotype, and the inabilityto taste it is recessive. If a taster woman with a nontasterfather marries a taster man who in a previous marriagehad a nontaster daughter, what is the probability thattheir first child will be(1) A nontaster girl(2) A taster girl(3) A taster boyb. What is the probability that their first two childrenwill be tasters of either sex?
Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood. The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that:a. all children will be normal b. at least two will be normal
Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood.The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that: a. all children will be normal b. at least two will be normal
Two mothers give birth to sons at the same time at a busy urbanhospital. The son of mother 1 has hemophilia, a disease causedby an X-linked recessive allele. Neither parent has the disease.Mother 2 has a son without hemophilia, despite the fact thatthe father has hemophilia. Several years later, couple 1 suesthe hospital, claiming that these two newborns were swappedin the nursery following their birth. As a genetic counselor, youare called to testify. What information can you provide the juryconcerning the allegation?
1. The pedigree chart in Figure 5.29 shows the inheritance of haemopiu family. Study the pattern of inheritance in the pedigree chart, and then answer the questions that follow. о 5 6. 3 8 9 10 11 Key Unaffected male Haemophiliac male О Unaffected female Fig. 5.29 Pedigree chart of a family affected by haemophilia a) What is the genotype and phenotype of individuals 2 and 4? b) (i) How many of the unaffected family members are definitely carriers of the recessive allele? (ii) How are you able to tell which of the family members are carriers? (4) (1) (3) c) (i) If Individual 11 marries a carrier female, what percentage of their sons is likely to be haemophiliacs? (1) (ii) Use a genetic diagram to show how you worked out your answer in i, (6) 2. Why is haemophilia never passed from father to son, even though it is most common in males? (4) 3. Can a mother pass on a sex-linked gene to her daughter? (1) 4. Sipho has red-green colour blindness. One of his grandfathers was also. colour…
In the human pedigree shown below, black filled symbols indicate individuals suffering from a rare genetic disease, whereas empty symbols represent people who do not have the disease. Based on the pedigree, what is the most likely mode of inheritance of this rare genetic disease? O Y-linked OX-linked dominant Autosomal recessive O Autosomal dominant OX-linked recessive
In the human pedigree shown below, black filled symbols indicate individuals suffering from a rare genetic disease, whereas empty symbols represent people who do not have the disease. Based on the pedigree, what is the most likely mode of inheritance of this rare genetic disease? Hodo O X-linked dominant OX-linked recessive O Autosomal dominant O Autosomal recessive Y-linked
Huntington’s disease, is an incurable neurodegenerative genetic disorder that affectsmuscle coordination and some cognitive functions, typically becoming noticeable inmiddle age. It results from an autosomal dominant gene (H) and there are no carriers ofthe disease. Two parents with Huntington’s disease have an affected child. What is theprobability that their next child will be an unaffected girl if they are not double-dominant?
a human disease known as cystic fibrosis is inherited as a recessive trait.Two unaffected individuals have a first child with the disease. What isthe probability that their next two children will not have the disease?