Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 13P
Summary Introduction
To determine: How can an autosomal dominant disorder explained through the pedigree.
Introduction: Autosomal means the errors occur on the autosomes (not sex chromosomes) of a person. Human beings contain 22 pairs of autosomes and one pair of sex chromosomes. In the case of autosomal dominant disease, one copy of the gene is sufficient to cause the disease. Some examples of autosomal dominant disorders are Huntington's disease and neurofibromatosis.
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Chapter 2 Solutions
Introduction to Genetic Analysis
Ch. 2 - Prob. 1PCh. 2 - Prob. 2PCh. 2 - Prob. 3PCh. 2 - Prob. 4PCh. 2 - Prob. 6PCh. 2 - Prob. 7PCh. 2 - Prob. 8PCh. 2 - Prob. 9PCh. 2 - Prob. 10PCh. 2 - Prob. 11P
Ch. 2 - Prob. 12PCh. 2 - Prob. 13PCh. 2 - Prob. 14PCh. 2 - Prob. 15PCh. 2 - Prob. 16PCh. 2 - Prob. 17PCh. 2 - Prob. 18PCh. 2 - Prob. 19PCh. 2 - Prob. 20PCh. 2 - Prob. 21PCh. 2 - Prob. 22PCh. 2 - Prob. 23PCh. 2 - Prob. 24PCh. 2 - Prob. 25PCh. 2 - Prob. 26PCh. 2 - Prob. 27PCh. 2 - Prob. 28PCh. 2 - Prob. 31PCh. 2 - Prob. 32PCh. 2 - Prob. 33PCh. 2 - Prob. 34PCh. 2 - Prob. 35PCh. 2 - Prob. 36PCh. 2 - Prob. 37PCh. 2 - Prob. 38PCh. 2 - Prob. 39PCh. 2 - Prob. 40PCh. 2 - Prob. 41PCh. 2 - Prob. 42PCh. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 44.1PCh. 2 - Prob. 44.2PCh. 2 - Prob. 44.3PCh. 2 - Prob. 44.4PCh. 2 - Prob. 44.5PCh. 2 - Prob. 44.6PCh. 2 - Prob. 44.7PCh. 2 - Prob. 44.8PCh. 2 - Prob. 44.9PCh. 2 - Prob. 44.10PCh. 2 - Prob. 44.11PCh. 2 - Prob. 44.12PCh. 2 - Prob. 44.13PCh. 2 - Prob. 44.14PCh. 2 - Prob. 44.15PCh. 2 - Prob. 45PCh. 2 - Prob. 47PCh. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 - Prob. 52PCh. 2 - Prob. 53PCh. 2 - Prob. 56PCh. 2 - Prob. 57PCh. 2 - Prob. 58PCh. 2 - Prob. 59PCh. 2 - Prob. 60PCh. 2 - Prob. 61PCh. 2 - Prob. 62PCh. 2 - Prob. 63PCh. 2 - Prob. 64PCh. 2 - Prob. 65PCh. 2 - Prob. 66PCh. 2 - Prob. 67PCh. 2 - Prob. 68PCh. 2 - Prob. 69PCh. 2 - Prob. 70PCh. 2 - Prob. 71PCh. 2 - Prob. 72PCh. 2 - Prob. 73PCh. 2 - Prob. 74PCh. 2 - Prob. 75PCh. 2 - Prob. 76PCh. 2 - Prob. 77PCh. 2 - Prob. 78PCh. 2 - Prob. 79P
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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forwardThe following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?arrow_forwardAn allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the allele if one parent does not carry it and the other is heterozygous?arrow_forward
- Is this pedigree recessive or dominant? Is it autosomal or sex-linked?arrow_forwardUsing the pedigree, assume that the disease is caused by an autosomal dominant allele, R. Give the genotype of the following individuals: (a) III-4 (the girl at lower right) (b) II-3 (the girl’s mother) (c) II-4 (the girl’s father)arrow_forwardFrom this pedigree is it dominant or recessive. Is ur autosomal or sex-linked?arrow_forward
- Ectrodactyly is a rare condition in which the fingers are absent, and the hand is split. It is usually inherited as an autosomal dominant trait. What do the double horizontal lines mean between III-1 and III-4? Is the pedigree below consistent with autosomal dominant inheritance?arrow_forwardNeurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a genetic son with NF1? Find the image attached.arrow_forwardChands syndrome is an autosomal recessive condition characterized by very curly hair, underdeveloped nails, and abnormally shaped eyelids. In the pedigree below: Which individuals must be carriers (heterozygotes)? ----- arrow_forward
- This is a typical pedigree for a family that carries neurofibromatosis. Is individual I-2 most likely homozygous or heterozygous? Why? Explain.arrow_forwardIn the following pedigree of an autosomal recessive disorder, what is the probability that IV-1 will be affected? I II III IV 1/2 1/12 O 3/4 2/3 O 1/4 Rr 1 R 2 Rr 2 R 3 RR 3 R 1 5 Rr 4 2arrow_forwardThe accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information. 1) What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AAAA and two of them are AaAa? (Hint: Consider all possible orders of genotypes.) Express your answer to two decimal places.arrow_forward
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