Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 13P
Summary Introduction

To determine: How can an autosomal dominant disorder explained through the pedigree.

Introduction: Autosomal means the errors occur on the autosomes (not sex chromosomes) of a person. Human beings contain 22 pairs of autosomes and one pair of sex chromosomes. In the case of autosomal dominant disease, one copy of the gene is sufficient to cause the disease. Some examples of autosomal dominant disorders are Huntington's disease and neurofibromatosis.

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Is this pedigree dominant or recessive. Which best defines this pedigree Autosomal or sex-linked?
Is this pedigree dominant or recessive? Autosomal or sex-linked? What is also usual about this pedigree?
Could the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.

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Introduction to Genetic Analysis

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