Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 8P
Summary Introduction
To determine: The stage of the life cycle of Drosophila in which meiosis occurs.
Introduction: Drosophila comes from the genus of flies, and the males of Drosophila have the longest sperms and are transferred to the females in the form of tangled coils. The fly is considered one of the best models for genetic researches.
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A male Drosophila melanogaster has the genotype A/a; B/b; C/c; XD/Y (all genes are on separate chromosomes). How many different sperm genotypes can it produce through meiosis of one single pre-gametic (2n) cell? (remember, there is no crossing over in male Drosophila)
Explain.
A reciprocal translocation between chromosome 1 and 2 in Drosophila resulted in AB//CPQR
and MN//ODEF. Double stroke indicates centromere location.
(i)
Diagram the alignment of these chromosomes during meiosis.
(ii)
What will be the gametes produced by alternate segregation, adjacent 1
segregation and adjacent 2 segregation?
Shown below are photomicrographs of Rhoeo tradescantia cells undergoing meiosis. Answer the following question for each of the photomicrographs:
Identify the cytogenetic abnormality observed (ex. ring, chain, laggard, bridge).
Identify the meiotic stage in which these aberrations are observed (as shown in the photomicrograph).
Explain how these aberrations are formed and relate to the possible causal mutation(s).
Will this result to sterile and/or fertile gametes? Explain.
Chapter 2 Solutions
Introduction to Genetic Analysis
Ch. 2 - Prob. 1PCh. 2 - Prob. 2PCh. 2 - Prob. 3PCh. 2 - Prob. 4PCh. 2 - Prob. 6PCh. 2 - Prob. 7PCh. 2 - Prob. 8PCh. 2 - Prob. 9PCh. 2 - Prob. 10PCh. 2 - Prob. 11P
Ch. 2 - Prob. 12PCh. 2 - Prob. 13PCh. 2 - Prob. 14PCh. 2 - Prob. 15PCh. 2 - Prob. 16PCh. 2 - Prob. 17PCh. 2 - Prob. 18PCh. 2 - Prob. 19PCh. 2 - Prob. 20PCh. 2 - Prob. 21PCh. 2 - Prob. 22PCh. 2 - Prob. 23PCh. 2 - Prob. 24PCh. 2 - Prob. 25PCh. 2 - Prob. 26PCh. 2 - Prob. 27PCh. 2 - Prob. 28PCh. 2 - Prob. 31PCh. 2 - Prob. 32PCh. 2 - Prob. 33PCh. 2 - Prob. 34PCh. 2 - Prob. 35PCh. 2 - Prob. 36PCh. 2 - Prob. 37PCh. 2 - Prob. 38PCh. 2 - Prob. 39PCh. 2 - Prob. 40PCh. 2 - Prob. 41PCh. 2 - Prob. 42PCh. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 44.1PCh. 2 - Prob. 44.2PCh. 2 - Prob. 44.3PCh. 2 - Prob. 44.4PCh. 2 - Prob. 44.5PCh. 2 - Prob. 44.6PCh. 2 - Prob. 44.7PCh. 2 - Prob. 44.8PCh. 2 - Prob. 44.9PCh. 2 - Prob. 44.10PCh. 2 - Prob. 44.11PCh. 2 - Prob. 44.12PCh. 2 - Prob. 44.13PCh. 2 - Prob. 44.14PCh. 2 - Prob. 44.15PCh. 2 - Prob. 45PCh. 2 - Prob. 47PCh. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 - Prob. 52PCh. 2 - Prob. 53PCh. 2 - Prob. 56PCh. 2 - Prob. 57PCh. 2 - Prob. 58PCh. 2 - Prob. 59PCh. 2 - Prob. 60PCh. 2 - Prob. 61PCh. 2 - Prob. 62PCh. 2 - Prob. 63PCh. 2 - Prob. 64PCh. 2 - Prob. 65PCh. 2 - Prob. 66PCh. 2 - Prob. 67PCh. 2 - Prob. 68PCh. 2 - Prob. 69PCh. 2 - Prob. 70PCh. 2 - Prob. 71PCh. 2 - Prob. 72PCh. 2 - Prob. 73PCh. 2 - Prob. 74PCh. 2 - Prob. 75PCh. 2 - Prob. 76PCh. 2 - Prob. 77PCh. 2 - Prob. 78PCh. 2 - Prob. 79P
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- A female Drosophila with the mutant phenotype 'notched wings' was mated to a wild type male. Two-thirds of the progeny were female. Half of the females had notched wings and the other half had wild type wings and all the male progeny had wild type wings. When the notched progeny were mated to their wild type brothers, the same results were obtained. Explain.arrow_forwardDuring metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is , or .For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is , or . In an organism with a haploid number of , how many possible combinations of maternal and paternal chromosomes can occur in its gametes? Select one: a. 72=49 b. 27=128 c.17=1 d. 214=16 384arrow_forwardWhich sex chromosome (X or Y) carries the gene for eye color in Drosophila?arrow_forward
- Meiosis is characterized by the pairing of homologouschromosomes during prophase I. In many species, an elaboratestructure called the synaptonemal complex forms betweenhomologues. During this pairing, homologues may exchangechromosomal material at sites called chiasmata. In meiosis I, thehomologues separate from each other, reducing the chromosomenumber to the haploid state (thus the reductive division). It isfollowed by a second division without replication, during whichsister chromatids become separated. The result of meiosis I and IIis four haploid cells. If sister chromatids separated at the first division, would meiosis still work?arrow_forwardButterflies have an X-Y sex-determination system that is different from that of flies or humans. Female butterflies may be either XY or X0, while butterflies with two or more X chromosomes are males. This photograph shows a tiger swallowtail gynandromorph, which is half male (left side) and half female (right side). Given that the first division of the zygote divides the embryo into the future right and left halves of the butterfly, propose a hypothesis that explains how nondisjunction during the first mitosis might have produced this unusual-looking butterfly. Question is also in the picture.arrow_forwardIn fruit flies, chromosomal crossing over does not occur in meiosis in males, whereas crossing over does occur in meiosis in females. In fruit flies that are heterozygous at many genes (i.e. many maternal and paternal versions of the genes differ), at what stage would cells no longer be heterozygous for any gene during the process of meiosis? a)After the second meiotic division in males, and after the first meiotic division in females. b)After the second meiotic division in both males and females. c)After the first meiotic division in both males and females. d)After the first meiotic division in males, and after the second meiotic division in females.arrow_forward
- In the haploid yeast Saccharomyces cerevisiae, the twomating types are known as MATa and MATα. You cross apurple (ad-) strain of mating type a and a white (ad+)strain of mating type α. If ad- and ad+ are alleles of onegene, and a and α are alleles of an independently inherited gene on a separate chromosome pair, what progenydo you expect to obtain? In what proportions?arrow_forwardWhat will be the number of chromosomes in Turner’s syndrome and Klinefelter's syndrome of an organism whose haploid number is 20arrow_forwardGenes A and B are on different chromosomes. An individual has the genotype: AaBb You sequence two gametes produced by this individual and find one gamete has the genotype AB, and one has the genotype Ab. How can this one individual (genotype AaBb) produce two gametes with different genotypes (AB or Ab)? Your answer should describe a specific process which occurs during meiosis. At what stage of meiosis does this process occur?arrow_forward
- Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?arrow_forwardConsider the following two meiocytes in metaphase I, with crossover positions as indicated for cell A. Solid black lines indicate spindle microtubules. Assume blue chromosomes represents paternal chromosomes and green maternal chromosomes. i) How many chromosomes and chromatids were present in cell A during the G1 phase? Please clearly specify chromosomes and chromatids in your answer. ii) For cell A, list all the gametes that will be produced from this cell. Give the alleles of each gamete contained within a set of brackets. You may ignore independent assortment.iii) For cell B, list all the gametes that will be produced from this cell given crossing over. Give the alleles of each gamete contained within a set of brackets. You may assume that no crossing over would take place.arrow_forwardIn Drosophila,, the curled mutation (cu, chromosome 3, position 50.0) results in wings that curl up, while ebony (e, chromosome 3, position 70.7) results in a dark body. True breeding, wild type females are mated with true breeding males with curled wings and ebony bodies. Considering Drosophila notation, which of the following correctly diagrams the P1 cross? X X ++ e + + + O+ X + X + ■ + X + + + 3+ X X X X + + Y Y cu cu cu + cu cu J e e e e e (D e + cu cu (Darrow_forward
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