Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 44.9P
Summary Introduction

To determine: The generalities that are assumed regarding the autosomal recessive disease.

Introduction: Autosomal recessive disorders are very rare. Some of the examples of the disorders are sickle cell anemia, cystic fibrosis, and Tay Sachs disease.

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One form of the bleeding disorder known as von Willebrand disease is an autosomal recessive disease. A man who is a carrier marries a woman who is also a carrier of the disease. (a) What percentage of their children are likely to have a disease phenotype? (b) What percentage of their children are likely to have a normal phenotype? (c) What percentage of their children are likely to be carriers of the disease?
For a recessive condition, two normal heterozygous individuals have children. What is the likelihood of their children being affected by this condition? What is the likelihood of their children being carriers without the condition? What is the likelihood of their asymptomatic children being carriers? Suppose that an individual with the condition has children with a heterozygous individual, what is the likelihood of their children being carriers?
In humans, albinism (lack of skin pigment) is an autosomal recessive trait. The first child of two normally pigmented parents is an albino. Which of the following is true about this family? SELECT ALL THAT ARE CORRECT. A) Their first child (described above) has a homozygous recessive genotype B) The next child born to this couple has a 25% chance of being albino. C) If the next child born to this couple is male, he has a greater chance of being albino. D) The parents are both heterozygous for albinism. E) The probability of their second child being albino is 0% F) If the second and third child born to this couple are albino, the fourth child has 100% chance of also being albino.

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Introduction to Genetic Analysis

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How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
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