Organic Chemistry: Structure and Function
Organic Chemistry: Structure and Function
8th Edition
ISBN: 9781319079451
Author: K. Peter C. Vollhardt, Neil E. Schore
Publisher: W. H. Freeman
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Chapter 8.8, Problem 8.21TIY

(a)

Interpretation Introduction

Interpretation: The synthesis of 2-methyl-2-propanol from methane should be written.

Concept introduction: Retrosynthetic analysis involves transformation of target molecule into simple precursor that can be used as substrate for the synthesis of target molecule. The bonds broken generate molecules called synthons or synthetic equivalent. The latter term is designated to indicate their use as substrate in synthesis. For instance, the synthons generated in phenylacetic acid are given as follows:

  Organic Chemistry: Structure and Function, Chapter 8.8, Problem 8.21TIY , additional homework tip  1

The best approach to retrosynthetic analysis is to look for easily available reagents such as Grignard reagents.

(b)

Interpretation Introduction

Interpretation: The synthesis of 3,4-dimethyl-3-hexanol from butane should be written.

Concept introduction:Retrosynthetic analysis involves transformation of target molecule into simple precursor that can be used as substrate for the synthesis of target molecule. The bonds broken generate molecules called synthons or synthetic equivalent. The latter term is designated to indicate their use as substrate in synthesis. For instance, the synthons generated in phenylacetic acid are given as follows:

  Organic Chemistry: Structure and Function, Chapter 8.8, Problem 8.21TIY , additional homework tip  2

The best approach to the retrosynthetic analysis is to look for easily available reagents such as Grignard reagents.

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(c)Show step by step how to synthesize methoxybenzene from benzene.
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