Interpretation:Compound that is intended for synthesis by student after aqueous workup should be given and the reason behind the unexpected formation of tertiary alcohol and the manner it is formed should be given.
Concept introduction:Grignard reagents are
Methyl bromide reacts with magnesium ether to give Grignard reagent. This Grignard methylmagnsium bromide on treatment with formaldehyde gives corresponding alcohol. The mechanistic pathway for the latter reaction is as follows:
The polar carbonyl bond breaks and the polar Grignard reagent attack at electron-deficient carbon. Finally with the hydrolysis and work up the alcohol is formed.
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Organic Chemistry: Structure and Function
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- Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning