(a)
Interpretation: The major organic product that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(b)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(c)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(d)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of
Analogous to the case that strong nucleophiles are more favored to react via
(e)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(f)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(g)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(h)
Interpretation: The major organic product(s) that would result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
(i)
Interpretation: The major organic product(s) that can result from the reaction of
Concept introduction: Carbocation formation is relatively slower than acid-base reactions. Carbocations generated from alkyl halides have two fates; they can be either trapped by nucleophiles to give substitution product or may deprotonate to yield a small amount of alkene. Stronger the base more is the probability of elimination over substitution over elimination. Further, if the still higher concentration is employed reaction proceeds via bimolecular elimination. On the other hand, the weak base waits until the carbocation is formed and the type of elimination with a relatively weak base is two-step elimination or
Analogous to the case that strong nucleophiles are more favored to react via
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Organic Chemistry: Structure and Function
- The nitro groups on the benzene ring in the reactant serve two purposes.One is to let you know what atoms in the reactant correspond to what atomsin the product. But what role do the nitro groups play electronically – whywould the reaction be much slower if these nitro groups weren’t attached tothose benzene carbons? Draw any relevant structures to support youranswer.arrow_forward• Same reagents as acid-catalyzed dehydration, except starting with a instead of an alcohol. • Same as the general mechanism hydrohalogenation, except with . Remember that EVERY acid-cat. mechanism begins with General Reaction: EXAMPLE: Provide H₂O H₂SO4 EXAMPLE: Provide the mechanism for the following addition reaction. H₂O H₂SO4 OH WH H₂O H₂SO4 as the nucleophile and ends with do PRACTICE: Provide the mechanism and predict the product of the following reaction. MAXOarrow_forward) Provide a reaction mechanism for the following reactions and name the major product for each. HBr H,SO4 HO,arrow_forward
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning