A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the autosomal inherited sickle cell anemia. She is married to a man who can see color normally and who is heterozygous for sickle cell trait. Using b (colorblind), B (normal color), S (normal hemoglobin), s (sickle cell), answer the following: a. What are the genotypes of the parents? b: What is the probability of having a child who is both color blind and has sickle cell anemia?

Complete a new Punnett square below, for a woman who is a carrier for sickle cell, who is married to a man who has sickle cell. What are the possible genotypes that you can identify, what is the ratio of phenotypes that are possible, and what is the chance that any of the offspring are affected by sickle cell anemia?

In humans, the genes for red-green color blindness (R = normal, r = color blind) and hemophilia A (H = normal, h = hemophilia) are both X-linked and only 3 map units apart. Suppose a woman has four sons, and two are color blind but have normal blood clotting and two have hemophilia but normal color vision. What is the probable genotype of the woman? HR/hr Hr/hr hr/hR Hr/hR HR/Hr

Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta  A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes.  Complete the Punnett square for the parental cross, and identify the possible…

Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a son with NF1? Record your answer as a value between 0 and 1 rounded to two decimal places.

Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body.   Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree).Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells.   Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_  HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA

Four children have the following blood types: A, B, AB, and O. Could these children have the same two biological parents?

A child has a blood type of “B positive”.  This child is known to be a heterozygote at the ABO blood type gene and also a heterozygote at the Rh blood type gene.  Select all of the choices below that show possible parents of this child. Question 7 options:   Genotypes  IA IA  X  IA IA   Genotypes  IA IA   X   IA i    Genotypes  IA i  X  IA i   Genotypes  IA IA  X  IA IB   Genotypes  IA IA  X  IB i   Genotypes  IA IA  X  i i   Genotypes  IA i  X  i i   Genotypes  IA i   X   IB i   Genotypes  IB IB  X   IB IB   Genotypes  IB IB  X  IB i   Genotypes  IB IB  X   IA i   Genotypes  IB IB  X   i i   Genotypes  IB i   X   IB i   Genotypes  IB i  X   i i   Genotypes  IB IB  X  IA IB   Genotypes  IA IA  X  IB IB   Genotypes  IA IB  X  IA IB   Genotypes  IA IB  X  IA i   Genotypes  IA IB  X   IB i   Genotypes  IA IB  X  i i   Genotypes   i i   X   i i   Genotypes  + +  X   + +     Genotypes  + +  X   + -…

Suppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.

It is determined that Elsa is experiencing beta-thalassemia major. Which of the following statements is NOT true regarding this diagnosis?   The cause of beta-thalassemia is genetic.   Beta-thalassemia major is a grave condition and has a high mortality rate.   Beta-thalassemia major is often treated with blood transfusions.   Because beta-thalassemia is an x-linked trait, it affects males more often than females.