(a)
Interpretation: The species
Concept introduction:
Leaving-group ability is determined by the capacity of leaving group to accommodate the negative charge as it is displaced from the alkyl halide. Among halogens, the iodides are best leaving groups followed by bromide chloride and fluoride. Besides halides, some sulphonates and sulphate that can easily delocalize the negative charge can also behave as good leaving group. These include tosylate, mesylate and triflate.
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups. Table for leaving groups on the basis of strength of bases are as follows:
(b)
Interpretation: The species
Concept introduction:
Leaving-group ability is determined by the capacity of leaving group to accommodate the negative charge as it is displaced from the alkyl halide. Among halogens, the iodides are best leaving groups followed by bromide chloride and fluoride. Besides halides, some sulphonates and sulphate that can easily delocalize the negative charge can also behave as good leaving group. These include tosylate, mesylate and triflate.
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups. Table for leaving groups on the basis of strength of bases are as follows:
(c)
Interpretation: The species
Concept introduction:
Leaving-group ability is determined by the capacity of leaving group to accommodate the negative charge as it is displaced from the alkyl halide. Among halogens the iodides are best leaving groups followed by bromide chloride and fluoride. Besides halides some sulphonates and sulphate that can easily delocalize the negative charge can also behave as good leaving group. These include tosylate, mesylate and triflate.
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups. Table for leaving groups on the basis of strength of bases are as follows:
(d)
Interpretation: The species
Concept introduction:
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups. Table for leaving groups on the basis of strength of bases are as follows:
(e)
Interpretation: The species
Concept introduction:
Leaving-group ability is determined by the capacity of leaving group to accommodate the negative charge as it is displaced from the alkyl halide. Among halogens, the iodides are best leaving groups followed by bromide chloride and fluoride. Besides halides, some sulphonates and sulphate that can easily delocalize the negative charge can also behave as good leaving group. These include tosylate, mesylate and triflate.
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups.
Nucleophillicity varies directly with negative charge, and also for elements that lie far left and bottom of the periodic table. It also increases with
(f)
Interpretation: The species
Concept introduction:
Leaving-group ability is determined by the capacity of leaving group to accommodate the negative charge as it is displaced from the alkyl halide. Among halogens, the iodides are best leaving groups followed by bromide chloride and fluoride. Besides halides, some sulphonates and sulphate that can easily delocalize the negative charge can also behave as good leaving group. These include tosylate, mesylate and triflate.
In general, the weak conjugate bases that are derived from strong acids are also good leaving groups. Table for leaving groups on the basis of strength of bases are as follows:
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Organic Chemistry: Structure and Function
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning