Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 7, Problem 36RA
Summary Introduction
To review:
The value of membrane potential at 1.5 msec (milliseconds) after the initiation of the action potential.
Introduction:
The difference observed in the electric potential between the inside and the outside of a cell is termed as membrane potential. The value of this potential usually ranges from -40 mV (millivolts) to -80 mV. The membrane potential has its highest significance in case of nerve cells.
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In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential.
Discuss the importance of threshold. How does this relate to the concept of APs being all or none?
Refer to the figure below to explain the mediation of action potentials by neurons using sodium and potassium channels at each of the six timepoints indicated.
The figure below may help in answering some of the questions.
1. What ions are flowing (and in which direction) both during the rising phase
and the falling phase of the action potential?
2. What are the values of both the 'y' (vertical) axis and the 'x' (horizontal) axis.
3. If extracellular levels of K+ rose (a condition called hyperkalemia), how would
that affect the resting membrane potential?
3
Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- Draw and label an action potential, indicating the ion movements responsible for the rising phase and the falling phase.arrow_forwardDefine an action potential.arrow_forwardConstruct a personalized flow chart and show the summary of the events involved for the propagation of action potential along the neuron. Highlight the role being played by ions.arrow_forward
- Sodium, chloride, and potassium ions are involved in setting up voltages across neuronal membranes. a. Describe a situation in which chloride ions can result in the same change in membrane potential as the sodium ions in the question above.arrow_forwardDraw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each) A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to restarrow_forwardAn action potential is considered an "all or nothing" event. What does this mean? Explain using the picture below to discuss what happens during each event. Use the letters in the diagram to match the events. +40- В -C 0- -40- E -60- -80- A 1 3 4 Time (msec) MAR 15 w MacBook Air 888 F2 F3 F4 F5 F7 FB F10 %23 24 & 3 4 6 8 %3D E T Y P 11 C V M command option Membrane potential (mV) .. ..arrow_forward
- Describe the “all-or-none” principle of action potentials. Does the restoration of a resting membrane potential depend on active or passive processes. Explain.arrow_forwardExplain the time course of the opening and closing of v-g Na+ and K+ channels during the action potential. How does that affect the ionic currents? COMMENTS : answer this question to best of your knowledge to understand the concept wellarrow_forwardConsider the following three diagrams of a nerve cell membrane. They show resting potential, depolarization, and hyperpolarization. Figure out which one is which, then draw them in the order they occur in a cell that undergoes an action potential outside + Na* inside K* Na* Nat K Nat K Na potential: -80 mV outside + Na K* Na* inside Na+ K Nat Na* K+ potential: +30 mV outside Na Na Na Na* K+ inside K* Na* Kt potential: -70 mVarrow_forward
- Summarize the steps in generating an action potential as a flowchart. You can make your flowchart on paper and take a picture of it, or make it electronically. Be sure you’ve included: the location in the neuron and components of the neuron involved, the types of cellular transport and ions involved, how action potentials can be stimulated and inhibited. you can get the information from this: https://youtu.be/HYLyhXRp298arrow_forwardDescribe the action potential in terms of the different functional states of the voltage- gated Na+ membrane channels (Note: there are three states)arrow_forwardShow a complete circuit diagram of the model of the neuron using the specific numerical values for each component: potassium ion concentration outside: 4.0 mmol/L potassium ion concentration inside: 77.5 mmol/Larrow_forward
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