Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 7, Problem 10CP
Summary Introduction
To review:
The function of acetylcholinesterase and its physiological significance.
Introduction:
To block the activity of postsynaptic cell, free ACh (acetylcholine) has to be inactivated immediately after the release of the same. The ACh inactivation is attained by acetylcholinesterase enzyme or AChE and it is present in the nerve terminals of both pre- and post-synaptic neurons and is bound to the membrane. It hydrolyzes acetylcholine into acetate and choline that can gain reentry into presynaptic terminal buttons to be further resynthesized into acetylcholine (ACh).
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Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- Distinguish between acetylcholine, an acetylcholine receptor, and acetylcholinesterase. State where each is foundand describe the function it serves.arrow_forwardMake a schematic diagram for the synthesis, storage, release, and degradation of acetylcholine.arrow_forwardConstruct a mechanism where sarin inhibits acetylcholinerase.arrow_forward
- Explain the chemical base of neurotransmitter..arrow_forwardIdentify the role of potassium in the propagation of an action potential and predict how a severe deficit of potassium in the body could affect muscle functionarrow_forwardA patient has been exposed to the organophosphate pesticide malathion,which inactivates acetylcholinesterase. Which of the following symptoms would you predict: blurring of vision, excess tear formation, frequent or involuntary urination, pallor (pale skin), muscle twitching, orcramps? Would atropine be an effective drug to treat the symptoms?(See Clinical Impact 16.2 for the action of atropine.) Explain.arrow_forward
- Sarin is an inhibitor of acetylcholinesterase. Draw a mechanism that shows this.arrow_forwardExplain in detail Muscarinic receptors in regards to the hisamine agonist. How do they cause smooth muscle contraction. Provide mechanismarrow_forwardExplain the use acetylcholine as a neurotransmitter?arrow_forward
- Define acetylcholine (ACh)arrow_forwardIdentify the important physiological structures involved in action potential; then, explain in detail how one nerve action potential causes one muscle action potential.arrow_forwardIn Neurology, please explain the relationship between suprathreshold depolarization and induced electrical neuro transmission. Is suprathreshold depolarization essential for inducing the electrical transmission?please explain in a few sentences.arrow_forward
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