Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Textbook Question
Chapter 7, Problem 20RA
In a step-by-step manner, explain how the voltage-regulated channels produce an action potential.
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Give a detailed, step-by-step description of the stages of an action potential, including a description of and explanation for the refractory periods and the rising and falling phases as well as return to rest. In your explanation, make sure to include 1) summation principles, 2) key membrane potentials (values), 3) location of voltage changes along the membrane, 4) states of the various voltage-gated channels. The more detail, the better. There are 5 main steps.
Name the three phases of an action potential. Describe for each the underlying molecular basis and the ion involved. Why is the term voltage-gated channel applied to Na+ channels involved in the generation of an action potential?
Refer to the graph showing the course of an action potential. Which of the numbered points along the graph represent the time when voltage-gated potassium channels are first activated?
a) 1
b) 2
c) 3
d) 4
e) 5
Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- Define an action potential.arrow_forwardConformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardList the two types of voltage-gated channels that playimportant roles in the production of action potentials.arrow_forward
- What would occur if voltage - regulated Na+ and k+ gates opened at the same time rather than at different times, during the production of an action potential?arrow_forwardMatch each type of membrane potential (resting, threshold, graded, or action) to its definition: a) The membrane potential at which voltage gated sodium channels open. b) The membrane potential that triggers the action potential. c) Change in membrane potential that may or may not reach threshold and that may be depolarizing or hyperpolarizing. d) Rapid, strong depolarization followed by immediate repolarization. This potential is self-renewing if the right ion channels are nearby.arrow_forwardSummarize the steps in generating an action potential as a flowchart. You can make your flowchart on paper and take a picture of it, or make it electronically. Be sure you’ve included: the location in the neuron and components of the neuron involved, the types of cellular transport and ions involved, how action potentials can be stimulated and inhibited. you can get the information from this: https://youtu.be/HYLyhXRp298arrow_forward
- Which types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forwardList the characteristics of a local potential versus an action potentials. Describe where each happens and what type of gates are involved and what is achievedarrow_forwardList the steps involved in the generation of an action potential.arrow_forward
- Based on the graph, the threshold voltage appears to be approximately. (Base your answer to this question on the graph below depicting an action potential.) +60 mV. +30 mV. 0 mV. −30 mV. −60 mV.arrow_forwardWhy is the propagation of action potential unidirectional?arrow_forwardList the series of events at the membrane that generate an action potential, including the contributions of chemically gated and voltage-gated ion channels?arrow_forward
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