Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 7, Problem 12RA
Summary Introduction
To determine:
The cause of hyperpolarization of the postsynaptic membrane in presence of glycine or GABA.
Introduction:
Hyperpolarization is due to the reduction of the membrane potential below the resting membrane potential. This takes place due to the action of amino acid neurotransmitters- GABA (gamma amino butyric acid) and glycine. Neurotransmitters are certain chemicals which are involved in the transmission of nerve impulse and they can be either excitatory or inhibitory.
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Hyperpolarization of the postsynaptic membrane in response to glycine or GABA is produced by the opening of a. Na+channels. b.K+channels. c.Ca 2+ channels. d.Cl− channels.
Glutamate's effect when it binds with protein receptors on the post synaptic membrane is to:
a. Initiate movement of potassium ions out of the membrane
b. Initiate movement of sodium ions into the membrane
c. Initiate movement of sodium ions out of the membrane
d. Initiate movement of potassium ions into the membrane
GABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired.
The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to:
a. hyperpolarize the postsynaptic membrane
b. decrease the threshold level
c. depolarize the postsynaptic membrane
d. maintain the resting potential
Calcium is vital for bone growth, but it's also an important part of neural transmission.
Calcium is required for the axon terminal to:
a. Reuptake the neurotransmitter via exocytosis
b. The neurotransmitter to be released by endocytosis
c. The neurotransmitter…
Postsynaptic potentials are graded potentials that develop in the postsynaptic membrane. Which one of the following statements accurately describes what causes EPSP's to occur at the postsynaptic membrane?
Group of answer choices
A.an EPSP results from the opening of voltage gated sodium channels
B.an EPSP results from the opening of chemically gated sodium channels
C.an EPSP results from the opening of voltage gated potassium channels
D.an EPSP results from the opening of chemically gated potassium channels
Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- A channel opens on a postsynaptic membrane that causes a negative ion to leave the cell. What type of graded potential is this? a. depolarizing b. repolarizing c. hyperpolarizing d. non-polarizingarrow_forwardCharge from depolarization along the axon reaches the axon terminal, but there is a lack of neurotransmitter release. Which of the following would cause this? Group of answer choices A. Lack of Na+ in the synaptic cleft B. Lack of Ca2+ in the synaptic cleft C. Reduced amount of K+ at the axon terminal D. Lack of voltage-gated sodium channels in the axon terminalarrow_forwardIn the hippocampus, when glutatmate is released into the synaptic cleft, but the postsynaptic cell is NOT depolarized, there is only a small postsynaptic response. Why is this the case? A. Ca++ ions block the NMDA ion channel B. Mg++ ions block the NMDA ion channel C. Glutamate is an inhibitory amino acid neurotransmitter D. There are no NMDA receptors on the postsynaptic cellarrow_forward
- GABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired. The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to: Select one: a. decrease the threshold level b. hyperpolarize the postsynaptic membrane c. depolarize the postsynaptic membrane d. maintain the resting potentialarrow_forwardPostsynaptic potential’s are graded potential’s that develop in the postsynaptic membrane. If the release of a neurotransmitter at a post synaptic membrane leads to hyper polarization, this event is referred to as A. EPSP B. ISIP C. Summation D. Facilitationarrow_forwardPostsynaptic potential’s are graded potential’s that develop in the postsynaptic membrane. If the release of a neurotransmitter at a post synaptic membrane leads to hyper polarization, this event is referred to as A. EPSP B. ISIP C. Summation D. Facilitation An individual EPSP usually only produces a slight depolarization of the postsynaptic membrane. If multiple stimuli arrive in rapid succession at a single synapse, this can lead to the generation of an action potential. This mode of generating action potentials is referred to as A. Spatial summation B. Facilitation c. Temporal summation D. Inhibition arrow_forward
- Mark the following statements as true or false. If a statement if false, correct it to make a true statement. a. An excitatory postsynaptic potential is caused by K+ or Clchannels opening in the membrane of the postsynaptic neuron. b. Postsynaptic potentials may summate by spatial summation in which multiple neurons fire onto a single postsynaptic neuron. c. An inhibitory postsynaptic potential causes the membrane potential of the postsynaptic neuron to approach threshold. d. Spatial summation can combine two EPSPs, two IPSPs, or an EPSP and an IPSParrow_forwardWhat's the consequence of glutamate release when the postsynaptic membrane expresses NMDA but not AMPA receptors? a. NMDA receptors conduct sodium in the absence of a membrane depolarization b. NMDA receptors couple to G-proteins; activation opens up downstream sodium channels c. Calcium passively diffuses into the neuron triggering neurotransmitter release d. Magnesium blocks the pore of the NMDA channel prohibiting sodium influxarrow_forwardOrganophosphate pesticides inhibit the action of acetylcholinesterase. What effect does this have in the cell? Select one: a. It prevents synthesis of ACh in the presynaptic terminal causing less neurotransmitter release b. It prevents breakdown of ACh in the synapse causing increased activity at the postsynaptic cell c. It prevents reuptake of ACh into the presynaptic terminal causing increased activity at the postsynaptic cell d. It prevents binding of ACh on the postsynaptic cell causing less activity e. It prevents reuptake of ACh into the presynaptic terminal causing less neurotransmitter synthesis.arrow_forward
- A neurotransmitter called "GABA" decreases the rate of action potential generation in neurons, but the effect can be overridden by excitatory neurotransmitters. Alcohol binds to the GABA receptor and has the same effect. Alcohol must Select one: a. Cause depolarization in neurons b. Cause hyperpolarization in neurons c. Block calcium entry at the axon terminus d. Block voltage-gated sodium channelsarrow_forwardUsing cable theory to describe axon conduction would tell us a. the larger the diameter of the axon the faster the propagation of the action potential b. the larger the diameter of the axon the slower the propagation of the action potential c. the smaller the diameter of the axon the faster the propagation of the action potential d. that having big axons is of no benefit and only takes up a lot of space e. the nervous system mainly has small axons because they are much faster than large onesarrow_forwardWhich of the following is true about the conduction of action potentials? a. Thicker axons are faster because there is more surface area on thicker axons. b. Myelin speeds conduction because the glial cells add voltage gated Na+ channels to the neuron. c. Diffusion of Na+ ions between the Nodes of Ranvier happens faster than the wave of opening and closing membrane proteins can travel. d. Neurons that don’t have myelin sheaths undergo saltatory conduction e. Action potentials move slowly.arrow_forward
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