Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 7, Problem 11RA
Summary Introduction
To determine:
The factor responsible for postsynaptic inhibition.
Introduction:
A synapse is a junction between two neurons where the nerve impulse is transmitted with the help of a neurotransmitter or electrical signals. This process follows the events of simultaneous depolarization and repolarization, which leads to the transmission of the nerve impulse.
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Hyperpolarization of the postsynaptic membrane in response to glycine or GABA is produced by the opening of a. Na+channels. b.K+channels. c.Ca 2+ channels. d.Cl− channels.
At an electrical synapse, presynaptic and postsynaptic membranes interface through a. neurofibril nodes. b. gap junctions. c. telodendria. d. neurotransmitters.
In the hippocampus, when glutatmate is released into the synaptic cleft, but the postsynaptic cell is NOT depolarized, there is only a small postsynaptic response. Why is this the case?
A.
Ca++ ions block the NMDA ion channel
B.
Mg++ ions block the NMDA ion channel
C.
Glutamate is an inhibitory amino acid neurotransmitter
D.
There are no NMDA receptors on the postsynaptic cell
Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- Glutamate's effect when it binds with protein receptors on the post synaptic membrane is to: a. Initiate movement of potassium ions out of the membrane b. Initiate movement of sodium ions into the membrane c. Initiate movement of sodium ions out of the membrane d. Initiate movement of potassium ions into the membrane GABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired. The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to: a. hyperpolarize the postsynaptic membrane b. decrease the threshold level c. depolarize the postsynaptic membrane d. maintain the resting potential Calcium is vital for bone growth, but it's also an important part of neural transmission. Calcium is required for the axon terminal to: a. Reuptake the neurotransmitter via exocytosis b. The neurotransmitter to be released by endocytosis c. The neurotransmitter…arrow_forwardGABA is an example of an inhibitory neurotransmitter. Drugs that increase the level of GABA are used to treat diseases such as epilepsy where the signal transmission needs to be impaired. The effect of the inhibitory neurotransmitter on the postsynaptic membrane is to: Select one: a. decrease the threshold level b. hyperpolarize the postsynaptic membrane c. depolarize the postsynaptic membrane d. maintain the resting potentialarrow_forwardWhich of the following is NOT an example of communication that happens from one neuron to another neuron? A. Endocrine signaling (ex. hormones secreted into the blood stream travel and bind to receptors on dstant cells). B. Retrograde neurotransmission (ex.the dendrite releases a neuroactive substance that binds to receptors on the axon terminal of a presynaptic neuron). C. Electrical communication via propagation of action potential from one node of ranvier to the next node of ranvier. D. Volume transmission (ex. neuropeptides diffuse away from the synapse and bind to receptors on adjacent cells) E. Electrical communication through gap junctions.arrow_forward
- Postsynaptic potential’s are graded potential’s that develop in the postsynaptic membrane. If the release of a neurotransmitter at a post synaptic membrane leads to hyper polarization, this event is referred to as A. EPSP B. ISIP C. Summation D. Facilitationarrow_forwardA channel opens on a postsynaptic membrane that causes a negative ion to leave the cell. What type of graded potential is this? a. depolarizing b. repolarizing c. hyperpolarizing d. non-polarizingarrow_forwardWhich of the following is (are) true about the myelin sheath? a. made of Schwann cells b. allow for saltatory conduction c. insulate the nerve cell d. all of thesearrow_forward
- Which of the following is an unlikely consequence of consistent or persistent synaptic firing in the CNS? a. Neural pruning b. Synaptic stabilization c. Long term potentiation d. Synaptic fatigue e. None of the above Checkarrow_forwardMark the following statements as true or false. If a statement if false, correct it to make a true statement. a. An excitatory postsynaptic potential is caused by K+ or Clchannels opening in the membrane of the postsynaptic neuron. b. Postsynaptic potentials may summate by spatial summation in which multiple neurons fire onto a single postsynaptic neuron. c. An inhibitory postsynaptic potential causes the membrane potential of the postsynaptic neuron to approach threshold. d. Spatial summation can combine two EPSPs, two IPSPs, or an EPSP and an IPSParrow_forwardRelatively high velocity (speed) action potential propagation is a feature of axons that have which of the following: a. additional mitochondria b. reduced absolute refractory period c. fewer potassium channels d. a myelin sheath Which effect listed below would characterize the drug as a serotonin agonist? a. Stimulating monoamine oxidase to reduce available serotonin b. Binding and activating a postsynaptic serotonin receptor c. Increasing the efficiency of a serotonin transporterarrow_forward
- Identify the following as properties of electrical synapses (ES), chemical synapses (CS), or both (B). a. _____ The plasma membranes of presynaptic and postsynaptic neurons are joined by gap junctions. b. _____ Transmission is unidirectional and delayed. c. _____ A presynaptic neuron and a postsynaptic neuron are involved. d. _____ The use of neurotransmitters packaged into synaptic vesicles is required. e. _____ Transmission is nearly instantaneous and bidirectionarrow_forwardThe two primary factors that influence the speed of an action potential propagation are axon diameter and a. myelination. b. the type of associated glial cell(s). c. concentration of K+ in the cell. d. the length of the axon.arrow_forwardThe axon hillock of a neuron reaches the threshold of excitation and the membrane potential becomes completely reversed. Then, suddenly, the membrane potential begins to return to resting membrane potential. What is the event that triggers this return to resting potential? A. Na+ channels close in a voltage-dependent manner B. Na+ channels close in a time-dependent manner C. Na+ channels close in a chemically-dependent manner D. Na+ channels open in a voltage-dependent mannerarrow_forward
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