Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 7, Problem 38RA
Summary Introduction
To review:
The approximate magnitude of IPSP (Inhibitory postsynaptic potential).
Introduction:
An inhibitory postsynaptic potential can be defined as a temporary hyperpolarization of the post synaptic membrane resulting from the flow of negatively-charged ions inside the postsynaptic cell. This is received in the situation when an inhibitory presynaptic cell which is connected to dendrite, starts firing an action potential. It occurs due to the opening of potassium or chloride channels.
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Students have asked these similar questions
A) What is the point A on the graph? Define this term.
B) What ions are moving at B on the graph, what direction are they moving and what type of channel is it?
C) What ions are moving at C on the graph, what direction are they moving and what type of channel is it?
D) If we used a chemical on the nerve at point B that prevented the channels for C from opening what would happen to the action potential?
Why does the velocity of nerve impulse conduction along the nerve decrease when the nerve is stretched? Answer in terms of physics.
In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential.
Discuss the importance of threshold. How does this relate to the concept of APs being all or none?
Chapter 7 Solutions
Human Physiology
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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- Define the refractory period in the propagation of action potential in two sentences. Give its importance then differentiate absolute and relative refractory period.arrow_forwardDraw and label an action potential, indicating the ion movements responsible for the rising phase and the falling phase.arrow_forwardBoth potassium and sodium channels located along the nerve membrane are voltage-gated. This means that they respond to the changes in the voltage by opening and closing the gates to allow the ions to flow in or out of the membrane. When the threshold level is reached and depolarization occurs, how come only the sodium ions begin to rush in? a. The threshold levels for both sodium and potassium channels are equal, but sodium channels are slower to open. b. The threshold levels for both sodium and potassium channels are equal, but potassium channels take longer to open. c. The threshold level for the potassium channels is lower than the sodium channels. d. The threshold level for the potassium channels is higher than the sodium channels.arrow_forward
- A nerve conduction velocity test measures nerve conduction velocity. In this test, an electrical stimulus is applied to a peripheral nerve and the length of time it takes for the corresponding muscle to contract is measured. Because the length of the nerve from stimulus point to muscle and the time it takes for the muscle to contract are both known, NCV can be calculated. This test result is helpful in distinguishing between different types of pathologies. For example, a patient with muscle weakness is being tested by a physician. There are three possible sources of the weakness: Disease of the muscle itself such as muscular dystrophy. In this condition, normal muscle tissue is replaced by adipose tissue and the muscle becomes incapable of contraction. Disease at the neuromuscular junction (NMJ) such as myasthenia gravis. This condition is described in the Skeletal Muscle Histology exercise and results from damage to the acetylcholine receptors on the muscle end plate. Disease…arrow_forwardConsider three alpha-motor neurons of different sizes: small, medium and large. All three neurons receive input from the same excitatory interneuron. When the interneuron fires action potentials at low frequency, only one alpha motor neuron fires action potentials. As the action potential frequency of the interneuron increases, two alpha-motor neurons are recruited, and at maximum frequency, all three are recruited. In what order would the three alpha-motor neurons have been recruited? Large first, then medium, then small. Small first, then medium, then large. Medium first, then small, then large. Medium first, then large, then small.arrow_forwardDescribe the resting potential for neurons. How is this potential established? Describe the development of the action potential. How does this come about, and what is the function of this phenomenon? Include a diagram of the various stages of the action potential, showing the changes in voltage that occur throughout this phenomenonarrow_forward
- The figure below may help in answering some of the questions. 1. What ions are flowing (and in which direction) both during the rising phase and the falling phase of the action potential? 2. What are the values of both the 'y' (vertical) axis and the 'x' (horizontal) axis. 3. If extracellular levels of K+ rose (a condition called hyperkalemia), how would that affect the resting membrane potential? 3arrow_forwardA laboratory experiment is set up where you have two fully functional nerves properly aligned so that it potentially can transmit an action potential through a synapse to the second nerve. The buffer outside the cells contain Na+, H+ and Cl- as the only inorganic ions. When you stimulate the nerve, surprisingly the second nerve does not respond. What is the most likely explanation for the failure of the second nerve response? State why you chose your answer. a. The lack of K+ in the buffer prevents propagation of the action potential b. Neurotransmitter is not being released into the synaptic space. c. An action potential can only be initiated by opening a ligand-gated channel. d. Although neurotransmitter is released, it is unable to stimulate opening of the second nerve' ligand-gated channel. e. Repolarization of the axon does not occur in this buffer.arrow_forwardUse this illustration to place these events in the order they occur during synaptic communication: Column A Column B a. Voltage gated sodium channels carry the action potential to the synapse by allowing the influx of sodium ions. 1. 1 2 b. An increase in calcium levels triggers vesicle release. 3. 3 c. Sodium enters the post-synaptic cell, causing it to depolarize. 4. 4 d. Sodium influx at the synapse activates voltage gated 5. calcium channels which allow calcium ions to enter the presynaptic neuron. 6. 6. e. Neurotransmitters are released into the synaptic cleft. f. Ligand-gated ion channels are opened by the neurotransmitters. 2.arrow_forward
- What is the approximate magnitude of the IPSP (how many mV)?What is the approximate magnitude of the EPSP (how many mV)?If the IPSP had not occurred, what would be the difference between the EPSP and the thresholdrequired to produce an action potential?arrow_forwardWhat causes Hyperpolarization following the spike of the action potential?arrow_forwardWhich of the following is TRUE regarding the absolute and relative refractory periods of the action potential (AP)? A. The absolute refractory period may be overcome if enough excitatory stimulation is applied to the neuronal membrane. B. The absolute refractory period is due the closing of the activation gate of voltage gated sodium channels at the peak of the AP. C. The relative refractory period is due to the closing of the activation gate of voltage gated potassium channels during the overshoot phase of the AP. D. The relative refractory period is due the closing of the inactivation gate of voltage gated sodium channels . E. All of the above statements are FALSE.arrow_forward
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