Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12, Problem 7P
| a. What letters are used to represent the short and long arms of human chromosomes? |
| b. Sketch a schematic diagram of a hypothetical chromosome 3 that has 3 regions with 2 bands each on the short arm and 5 regions with 3 bands each on the long arm. Label the arms, regions, and bands and indicate a gene at position 3p32. |
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Students have asked these similar questions
a. Manually, using a pencil, draw a cell in anaphase II from an organism in which 2n =
2 and each chromosome is metacentric.
b. Given that each G1 nucleus from this organism contains 16 picograms of DNA, how
many picograms of chromosomal DNA would you expect in the cell shown here?
Which types of chromosome mutations a. increase the amount of genetic material in a particular chromosome? b. increase the amount of genetic material in all chromosomes? c. decrease the amount of genetic material in a particular chromosome? d. change the position of DNA sequences in a single chromosome without changing the amount of genetic material? e. move DNA from one chromosome to a nonhomologous chromosome?
What types of chromosome mutations are required to change this chromosome into the following chromosomes? (In some cases, more than one chromosome mutation may be required.)
Q. A B • C F E D G
Chapter 12 Solutions
Genetics: From Genes to Genomes
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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- The size of one copy of the human genome is approximately 3 billion base pairs, and it contains about 27,000 genes organized into 23 chromosomes, a. Human chromosomes vary in size. What would you predict is the size of the average chromosome?arrow_forward● ● Illustrate the chromosome changes in interphase and mitosis using a diploid cell that is 2n=4 (two large and two small chromosomes). Label the circles as G1 and G2 stages of interphase and each phase of mitosis (in order). Draw the chromosome in each circle using the following guidelines. 1) For unreplicated chromosome draw a line (/) and for replicated chromosome draw an X. 2) For simplicity, do not indicate that the chromosomes are decondensed chromatin during interphase. 3) Skip drawing the nuclear membrane or spindle fibers, since we are focusing on the chromosomes. Label genes in the resulting daughter cells as A/a and B/b. (These letters represent genes which are at particular places along the DNA molecule. Each chromosomes can have a thousand genes but we are focusing on these two.) Ask me Qs in class if anythign on this is not clear.arrow_forwardColchicine is a chemical mutagen that inhibits the spindle formation and prevents anaphase, which retains the cell’s single restitution nucleus (doubled chromosome number). Suppose that an onion (2n=16) is subjected to three consecutive rounds of colchicine treatment, what will be the resulting chromosome number of the treated onion?arrow_forward
- Describe the function of the centromere. How are centromeres different from other regions of the chromosome?arrow_forwardIn Human chromosome 11 GC content is 42%. What is the percentage of each nucleotide on chromosome 11?arrow_forwardIn a germline progenitor cell before DNA replication (2N), a translocation occurred between a telocentric and submetacentric chromosome resulting in a translocation heterozygote. The location of the translocation is illustrated below. Draw the Prophase I pairing conformation that would result from this translocation. The four types of chromosomes you have now can be labeled as follows: T-WT (telocentric wild type), T-TL (telocentric translocation), SM-WT (submetacentric wild type), and SM-TL (submetacentric translocation). Using these labels, list (please do not draw) the possible outcomes of Anaphase I and the possible phenotypes for each outcome. Please explain your reasoning for each phenotype in a few words. asaparrow_forward
- The chromosomes drawn below are found in a human skin cell. The lines represent the chromosomes themselves. The letters indicate the location of a particular version of a gene. d) T/F If the protein produced by the BA gene is involved in the formation of ovaries, then the BA gene is likely located on a sex chromosome. e) T/F Because the genes shown here are found in skin cells, these genes code for proteins required for skin cell function.arrow_forward23 How would one best define the chromosomal location of a GENE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a located on a single chromosome located oWa pair of homologous chromosomes located on multiple chromosomes d. located on a pair of non-homologous chromosomesarrow_forwardIn tomato plants, the genes for fruit colour (C), fruit fructose content (F), fruit length (L), and plant height (H) are all found on chromosome 4. Map distances between the four genes are shown below. Genes Distance in Map Units H and F 40 F and L 12 C and F 75 L and C 87 L and H 52 Sketch and label a gene map to identify the order of the four genes on chromosome 1 in tomato plants.arrow_forward
- Could you please explain simple terms how does the base sequence contained in the telomeric regions of chromosomes differ from that found elsewhere in the chromosome?arrow_forwardARVC5 is a disorder characterized by the replacement of healthy heart tissue with fatty fibrous tissue. Recent research has discovered the mutated gene that causes the disorder is on chromosome 3. People who have the mutation have a GCG triplet instead of the normal ACA triplet. The following is a section of a gene on chromosome 3: GGT GCG ACA ATT 1. Complete the following table. AA DNA sense strand DNA antisense strand GGT GCG ACA ATT mRNA tRNA 2. Indicate the change in the amino acid sequence resulting from the mutation in the gene described above., B I 123 ||| 14 E GO LG US X₂ x²arrow_forwardWhat is the approximate location of the centromereon human chromosome 7?arrow_forward
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License