Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 12, Problem 12P
| a. | Drosophila | |
| b. | Humans | |
Give examples of constitutive and facultative heterochromatin in:
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Chapter 12 Solutions
Genetics: From Genes to Genomes
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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- Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forwardb. An example of autosome and heterochromosome c. An example of homologous chromosome, sister chromatid and centromere. d. The total number of chromosomes in a metaphase kangaroo cell. e. A sentence to explain the difference between the terms gene and allele that might apply to this species. 5) Suppose that in a species of flowering plant, we cross a plant with red flowers with a short stem with a plant with blue flowers with a long stem. The offspring all have mauve flowers and a long stem. The two characters, flower color and stem length, are found on different chromosomes. What can you conclude about the mode of inheritance of each of the characteristics of this plant species? Incomplete dominance or codominance: C"C", simple A/a dominance b If a progeny with long-stemmed mauve flowers from FI is crossed with a plant with short-stemmed mauve flowers, what proportion of the progeny will have the same genotype as either of the parents? Compulsory Punnett grid. ONA and the principles…arrow_forwardWrite the word TRUE if the statement is correct and if false, replace the underlined words with the correct one. 1. Heterochromatin is typically gene-rich and composed of loosely-packed DNA that is transcriptionally active. 2. Molecular switches regulate the expression of genes by directing where and when genes should be turned on or off depending on the cell signal. 3. DNA Methylation and acetylation of histones are inverselycorrelated 4. Specialized cells produce specialized proteins derived from luxury genes which are constitutively expressed. 5. In mammals, methylation patterns that regulate DNA structure and gene expression become evident from the gastrula stage.arrow_forward
- Discuss the role/relevance of chromatin in the storage, expression and transmission of genetic materialarrow_forwardexplain Scope of heterochromatin effects?arrow_forwarda. For the E.coli haploid genotype below, determine the phenotype for the following proteins. Assume that any genes or structural elements not shown are wildtype. lacls lacz lacY+ lacz uninducible lacY uninduciblearrow_forward
- Describe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.arrow_forwardI. The retinoic acid receptor (RAR) is a transcription factor that is similar to steroid hormone receptors. Thesubstance (ligand) that binds to this receptor is retinoicacid. One of the genes whose transcription is activatedby retinoic acid binding to the receptor is myoD. Thediagram that follows shows a schematic view of theRAR proteins produced by genes into which one oftwo different 12-base double-stranded oligonucleotides had been inserted in the ORF. The insertion site(a–m) associated with each mutant protein is indicatedwith the appropriate letter on the polypeptide map.For constructs encoding proteins a–e, oligonucleotide 1(5′ TTAATTAATTAA 3′ read off either strand) wasinserted into the RAR gene. For constructs encoding proteins f–m, oligonucleotide 2 (5′ CCGGCCGGCCGG 3′)was inserted into the gene.NH2 f g h i j k l m COOHa b c d eThe wild-type RAR protein can both bind DNA and activate transcription weakly in the absence of retinoic acid(RA) and strongly in RA’s presence. Each…arrow_forwardWhich of the following represents the order of increasingly higher levels of organization of chromatin? Select one: O a. looped domain, nucleosome, 30-nm chromatin fiber O b. 30-nm chromatin fiber, nucleosome, looped domain C. nucleosome, looped domain, 30-nm chromatin fiber O d. looped domain, 30-nm chromatin fiber, nucleosome nucleosome, 30-nm chromatin fiber, looped domain е.arrow_forward
- Consult Figure 2. Would you consider this figure to be depicting euchromatin, or heterochromatin, both, or neither? Explain your choice.arrow_forwardMatch the type of chromatin with the chromosome structure or region. chromatin of telomeres v Choose... facultative heterochromatin constitutive heterochromatin chromatin of centromeres eychromatinarrow_forwardExplain the fate of transferred chromosomal DNA ifrecombination does not occur in the recipient cell.arrow_forward
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