Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 12, Problem 25P

If you are comparing the two telomeres in each entry in the following list, in which cases would you expect the

Two telomeres always to have exactly the same number of TTAGGG repeats?

a. One telomere at one end of a chromosome, one telomere at one end of a nonhomologous chromosome.
b. One telomere at one end of a chromosome, o ne telomere at the corresponding end of the homologous
chromosome
c. One telomere at one end of a chromosome, the other telomere at the other end of the same chromosome
d. One telomere at one end of a chromatid, the other at the corresponding position in the sister
chromatid
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If you are comparing the two telomeres in each entryin the following list, in which cases would you expectthe two telomeres always to have exactly the samenumber of TTAGGG repeats?a. One telomere at one end of a chromosome, one telomere at one end of a nonhomologous chromosome.b. One telomere at one end of a chromosome, onetelomere at the corresponding end of the homologous chromosome.
In a germline progenitor cell before DNA replication (2N), a translocation occurred between a telocentric and submetacentric chromosome resulting in a translocation heterozygote. The location of the translocation is illustrated below.     Draw the Prophase I pairing conformation that would result from this translocation.  The four types of chromosomes you have now can be labeled as follows: T-WT (telocentric wild type), T-TL (telocentric translocation), SM-WT (submetacentric wild type), and SM-TL (submetacentric translocation). Using these labels, list (please do not draw) the possible outcomes of Anaphase I and the possible phenotypes for each outcome. Please explain your reasoning for each phenotype in a few words.    asap
The two telomeric loop structures are formed by invasion of the 3' single-strand overhang. Draw the two loop structures and describe why it is important to have these structures at the end of the chromosomes.

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Genetics: From Genes to Genomes

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