Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12, Problem 3P
What difference exists between the compaction of chromosomes during metaphase and interphase? Give at least one reason why this difference may be necessary.
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Chapter 12 Solutions
Genetics: From Genes to Genomes
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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- Define the following terms: a. chromosome b. chromatinarrow_forwardList in each blank the description of events associated with each stage of mitosis in addition to the preparatory stage Interphase. Some events and structures occur only in plant cells and some in animal cells. Mark these events in the list with an asterisk.arrow_forwardThe interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin. a) What is chromatin? b) How can the chromatin structure change?arrow_forward
- Why interphase is called prepering phase?arrow_forwardHuman somatic cells have 46 chromosomes. Are the cells different in any way from the parent cell and what is chromosome count of each of those cells once they have finished mitosis?arrow_forwardWith regard to thickness and length, what do you think chromosomes would look like if you microscopically examined them during interphase? How would that compare with their appearanceduring metaphase?arrow_forward
- A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 20 picograms of DNA per nucleus. Approximately how many picograms of DNA would be found in a nucleus at prophase of mitosis?arrow_forwardDraw and label G1 and G2 stages of interphase and each stage of mitosis (in order) for a cell that has two large and two small chromosomes, 2n=4. For unreplicated chromosome draw a line ( / ) and for replicated chromosome draw an X. Since we are focusing on the DNA, you can skip drawing the nuclear membrane or spindle fibers. For simplicity, do not indicate that the chromosomes are decondensed chromatin during interphase. Mark and label a place on one of the large chromosomes with the dominant allele of the “A” gene and put the recessive allele “a” on the other homolog. Mark and label a place on one of the small chromosomes with allele “B” and put the recessive allele “b” on the other homolog.arrow_forwardConsider how histone proteins bind to DNA and then explain whya high salt concentration can remove histones from DNA (asshown in 10.18b).arrow_forward
- The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes. Since few genes exist there, these regions almost never decondense for transcription. At what point during the cell cycle would expect to observe decondensation of heterochromatic regions? Why?arrow_forwardWhy do eukaryotic cells need to go through the elaborate procedure of mitosis rather than simply dividing during interphase? Select as many answers as apply. 1.Daughter cells must be genetically identical to the mother cell, for homeostasis and ordered tissue growth. 2.Bivalent chromosomes must condense and be separated in an orderly fashion, to allow equal distribution of copies into daughter cells 3.Physically dividing the nucleus during interphase would likely lead to gross chromosome breakage and highly unequal assortment of genetic information into daughter cells. 4.Dividing the nucleus during interphase would have the same outcome as mitosis 5.Daughter cells must have half the number of chromosomes after mitosis than the mother cells 6.The homologous pairs of chromosomes need to be separated, to ensure copies go to the daughter cells.arrow_forwardIf a bacterial chromosome were inserted into a eukaryotic cell, would it be stable? Would it segregate like eukaryotic chromosomes do during mitosis and meiosis? Why or why not?arrow_forward
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