Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 11, Problem 8Q
Summary Introduction
To review:
The noncovalent interactions that promote the stability as well as functional properties of biological membranes.
Introduction:
A biological membrane is composed of phospholipids and proteins that are arranged in a bilayer. Phospholipids are amphipathic molecules and are present in a bilayer, the hydrophilic heads face outward and interact with the aqueous medium on both sides of the bilayer, whereas the hydrophobic tails face each other and are directed toward the core of the bilayer.
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Describe the types of noncovalent interaction
that promote the stability and the functional
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Explain the following statement: The structure of all biomembranes depends on the chemical properties of phospholipids, whereas the function of each specific biomembrane depends on the specific proteins associated with that membrane.
Describe the structure and function of the three types of junctions found between cells.
Chapter 11 Solutions
Biochemistry: The Molecular Basis of Life
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- Knowing that there is constant turnover of phospholipids in a cell’s membrane and that new phospholipids are regularly synthesized, what strategy could a cell (or organism) use to maintain membrane fluidity and integrity in: A) Cold temperatures? B) Hot temperatures?arrow_forwardList the following compounds in order of increasing lipid bilayer permeability: RNA, Ca2+, glucose, ethanol, n2, water.arrow_forwardExplain Cholesterol and Sphingolipids Cluster with Specific Proteins in Membrane Microdomains.arrow_forward
- Below are listed molecules with different chemical characteristics. Knowing that all molecules will eventually diffuse across a phospholipid bilayer, select the list that most accurately predicts the relative rates of diffusion of these molecules (fastest to slowest) across a biological membrane. alanine, propanol, sodium, estrogen sodium, propanol, alanine, estrogen estrogen, propanol, sodium, alanine estrogen, propanol, alanine, sodiumarrow_forwardExplain the structure of a biological membrane. Be sure to address how the phospholipids, proteins, glycolipids and glycoproteins are organized to create the biological membrane.arrow_forwardAccording to the fluid mosaic model of cell membranes, which of the following is a true statement about membrane phospholipids? They frequently flip-flop from one side of the membrane to the other. They have hydrophilic tails in the interior of the membrane. They can move laterally along the plane of the membrane. They are free to depart from the membrane and dissolve in the surrounding solution.arrow_forward
- Please describe the hydrophobic effect and its contribution to membrane protein folding.arrow_forwardDescribe some of the activities performed by membrane proteins in multicellular organisms.arrow_forwardDescribe the Fluid-Mosaic Model of membrane structure. Indicate the hydrophobic and hydrophilic regions of the membrane and give examples of various membrane proteins.arrow_forward
- Name the three groups into which membrane-associated proteins may be classified. Explain the mechanism by which each group associates with a biomembrane.arrow_forwardExplain how the following affect membrane fluidity:– Level of phospholipid tail saturation– Level of cholesterol– Phospholipid tail lengtharrow_forwardA transmembrane protein has the following properties: it has two binding sites, one for solute A and one for solute b. The protein can undergo a conformational change to switch between two states: either both binding sites are exposed exclusively on one side of the membrane or both binding sites are exposed exclusively on the other side of the membrane. The protein can switch between the two conformational states only if both binding sites are occupied or if both binding sites are empty, but cannot switch if only one binding site is occupied. What kind of protein do these properties define?arrow_forward
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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license