Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 11, Problem 62TQ
Summary Introduction
Introduction:
Phospholipids are anessential part of the plasma membrane. These are amphipathic molecules and contain both polar and nonpolar groups. The hydrophilic domain known as polar head group contains phosphate and the hydrophobic part is composed of large hydrocarbon chains of fatty acids.
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Chapter 11 Solutions
Biochemistry: The Molecular Basis of Life
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- Bacterial phospholipids are hydrophobic due to fatty acids, while archaeal phospholipids are hydrophobic due to ______________________________.arrow_forwardHydrophobic polypeptides that dissipate osmotic gradients by inserting themselves into a membrane to form a channel are called _____________.arrow_forwardSAM is a donor of _____________ groups in the synthesis of some phospholipid molecules.arrow_forward
- The antifungal drug nystatin kills fungal cells in part through formation of membrane pores that cause K+ leakage. To what class of membrane-inserting molecules does nystatin belong?arrow_forwardQuestion 8 of 26 Suppose a drug molecule binds to a protein target. Complete the table which describes possible noncovalent interactio (NCI) in the binding site. Assume the drug has a variety of types of polar and nonpolar regions. Type of NCI ionic interaction dipole-dipole Species able to form that NCI any species with permanent dipoles (C=O, etc.) H bonded to N, O, or F and a lone pair on N.O.or F Answer Bank dielectric size; type of charge ions; charged species hp dispersion Parameters affecting the NCI hydrogen bond strength and orientation of dipole orientation polarizability; size; molecular weightarrow_forwardQuestion 104 is an irreversible competitive inhibitor of bacterial beta-lactamase. rifampin O trimethoprim clavulanic acid O sulfamethoxazolearrow_forward
- Question 2 Pheneticillin (below) is a B-lactamase sensitive penicillin. Draw the structure of the inactive form of the drug after enzymatic hydrolysis. N OHarrow_forward_____________ is a polymeric network in the prokaryotic cell wall in which short peptide chains are linked to carbohydrate chains.arrow_forwardQuestion 26 The removal of a phosphate from cytidine yields the cytosine base. A) True B Falsearrow_forward
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