Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 8, Problem 8RQ
Summary Introduction

To review:

The degeneracy of genetic code and the wobble in codon-anticodon recognition.

Introduction:

Genetic codes are used to interpret the information encoded within genetic material like DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) into proteins. During protein synthesis, these codes define the mapping of codons which are tri-nucleotide sequences and amino acids.

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What could be the effect of a deletion, substitution or addition that alters the sequence of the stop codons?
a) What is a mutation in molecular terms?      b) a mutation deletes a base in the genomic DNA discuss how that will affect the reading frame and expression product production. Using the following list of codons describe, using diagrams etc., how information stored in the DNA is translated into a peptide. Be sure to discuss all steps. In other words, use a diagram and give me sequences, transcription and translation steps. Show the sequences of the sense and the other DNA strand, the mRNA and the tRNA’s.                    UUU -phenylalanine         UCU -serine          AUG –initiation/methionine                CUU -leucine                    ACU -threonine                   GUU -valine                      UAA -Termination
The E site may not require codon recognition. Why?
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DNA vs RNA (Updated); Author: Amoeba Sisters;https://www.youtube.com/watch?v=JQByjprj_mA;License: Standard youtube license