Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 24.2, Problem 2TQ
Summary Introduction
To review:
The type of antibodies that are taken up by type IgG of subject 2 when the raise from subject 1 is injected into it.
Introduction:
IgG stands for immunoglobulin G, one of the antibody types. It is present in abundance by contributing approximately 70-75% of antibodies in the human body. It is a common type of antibody present in blood circulation and a major component of the humoral type of immunity. This type of antibody helps in protection against pathogenic infection by memorizing the type of germs encountered before.
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What is an introduction to ANTIBODY STRUCTURE AND FUNCTION ? How would you summarize this to someone who is new to this?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726606/
You just received the properly labeled blood bank specimen on patient Aran Stark. You decide to collect some background information about her known historical antibodies before beginning the work-up knowing that she has a history of anti-E, anti-K, anti-Jk^a, anti-Fy^a, anti-M and anti-Le^a.
Which antibody reactivity is enhanced by acidification?
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Chapter 24 Solutions
Microbiology: An Evolving Science (Fourth Edition)
Ch. 24.1 - Prob. 1TQCh. 24.1 - Prob. 2TQCh. 24.1 - Prob. 3TQCh. 24.2 - Prob. 1TQCh. 24.2 - Prob. 2TQCh. 24.2 - Prob. 3TQCh. 24.2 - Prob. 4TQCh. 24.2 - Prob. 5TQCh. 24.3 - Prob. 1TQCh. 24.3 - Prob. 2TQ
Ch. 24.3 - Prob. 3TQCh. 24.4 - Prob. 1TQCh. 24.4 - Prob. 2TQCh. 24.5 - Prob. 1TQCh. 24.5 - Prob. 2TQCh. 24.6 - Prob. 1TQCh. 24.6 - Prob. 2TQCh. 24 - Prob. 1RQCh. 24 - Prob. 2RQCh. 24 - Prob. 3RQCh. 24 - Prob. 4RQCh. 24 - Prob. 5RQCh. 24 - Prob. 6RQCh. 24 - Prob. 7RQCh. 24 - Prob. 8RQCh. 24 - Prob. 9RQCh. 24 - Prob. 10RQCh. 24 - Prob. 11RQCh. 24 - Prob. 12RQCh. 24 - Prob. 13RQCh. 24 - Prob. 14RQCh. 24 - Prob. 15RQCh. 24 - Prob. 16RQCh. 24 - Prob. 17RQCh. 24 - Prob. 18RQCh. 24 - Prob. 19RQCh. 24 - Prob. 20RQCh. 24 - Prob. 1TQCh. 24 - Prob. 2TQCh. 24 - Prob. 3TQCh. 24 - Prob. 4TQCh. 24 - Prob. 5TQ
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- What is Natural antibodies?arrow_forwardWhat is meant by the “window” regarding antibody presence in the blood?arrow_forwardIf you are transfusing blood to a hypothetical patient, is it more important that the transfused blood have antigens that will not react with the recipient’s antibodies or antibodies that will not react with the recipient’s antigens? Pick one and briefly explain why.arrow_forward
- Draw a schematic diagram of a typical IgG molecule and label each of the following parts: H chains, L chains, intrachain disulfide bonds, hinge, Fab, Fc, and all the domains. Indicate which domains are involved in antigen binding.arrow_forwardWith the aid of diagrams, discuss the role of autoantibodies in three named autoimmune diseases, then discuss how four named monoclonal antibody therapies (biologics) have been used to treat patients with autoimmunity in 2000 words.arrow_forwardWhat are ABO blood-group antigens?arrow_forward
- When a helper T cell releases interleukin-1 to stimulate other leukocytes during antigen presentation, interleukin-1 is acting as a(n):arrow_forwardIn terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?arrow_forwardAddition of immunoglobulin G (IgG) specific for hemoglobin to a solution of hemoglobin results in the formation of a red precipitate. In contrast, addition of the Fab fragments from this antibody to hemoglobin results in no such precipitate. What could explain this difference in results? Treatment with papain produces Fab fragments with different antigen specificity than the original IgG molecule. IgG can simultaneously bind two different antigens, whereas an Fab fragment can only bind one antigen at a time. The Fab fragments preferentially bind to other Fab fragments rather than to hemoglobin. The hemoglobin molecule antibody-binding sites can bind IgG molecules, but cannot bind Fab fragments.arrow_forward
- A person with type A+ blood gets a transfusion with type O- blood. What is most likely to happen to the recipient? A) The recipient's blood will agglutinate (clump) due to the presence of natural antibodies in the recipient's blood. B) Nothing because the donor's blood is compatible with the recipient's blood. C) The recipient's blood will agglutinate (clump) due to the presence of natural antigens on the recipient's blood cells.arrow_forwardConsider a pencil-shaped protein with two epitopes, Y (the “eraser” end) and Z (the “point” end). They are recognized by antibodies A1 and A2, respectively. Draw and label a picture showing the antibodies linking proteins into a complex that could trigger endocytosis by a macrophage.arrow_forwardWhat is an immunoglobulin? Describe the structure of an immunoglobulin molecule (light chain and heavy chain).arrow_forward
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