Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 24.1, Problem 3TQ
Summary Introduction
To review:
The immunological differences in protein with the same target and the inability of antibodies that direct against one rhinovirus strain to block the attachment of the other rhinovirus strain.
Introduction:
Rhinovirus is the causative agent for common cold in humans. It has three species that show differences on the basis of their surface proteins. These viruses have a very small size and possess lytic nature. Rhinovirus is one of the major reasons for respiratory problems in children as well as in adults.
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Students have asked these similar questions
1) 286 individuals were newly diagnosed with Human Immunodeficiency Virus in 2018 in Minnesota. Of these
individuals, 76% were male. HIV is an enveloped, ssRNA virus_ Baltimore classification VI. This virus targets CD4+
cells. CD4 refers to a glycoprotein which serves as a co-receptor for T-cells, located on T-helper and T-reg immune cells.
a) What part of the HIV virus allows for specificity to CD4+ cells?
Let’s say there are two closely related viruses, let’s call them Guernsey virus and Micro virus. These two viruses only infect epithelial cells. Their surface antigens are sufficiently similar that there are a number of shared epitopes between the two viruses. Choose one of the following:
A) If you get infected and successfully recover from one virus, it’s quite possible that you’ll have neutralizing antibodies against the other.
B) If you get infected and successfully recover from one virus, you’ll still be susceptible to the other one because the antigens aren’t exactly the same.
C) If you get infected and successfully recover from one virus, it’s likely that getting infected with the other virus will be worse because of the common phenomena of antibody-dependent enhancement.
D) Not enough information has been given.
Which of the following is false when considering the CCR5Δ32 mutation?
a) The mutation prevents the entry of HIV-1 into a T cell.
b) The deletion that produced CCR5Δ32 caused a frameshift which extends the length of the protein product.
c) CCR5Δ32 prevents infection by HIV-1 in homozygotes but only delays the onset of HIV symptoms in heterozygotes.
d) The protein product produced by CCR5Δ32 is altered in such a manner that it cannot embed in the cell membrane.
Chapter 24 Solutions
Microbiology: An Evolving Science (Fourth Edition)
Ch. 24.1 - Prob. 1TQCh. 24.1 - Prob. 2TQCh. 24.1 - Prob. 3TQCh. 24.2 - Prob. 1TQCh. 24.2 - Prob. 2TQCh. 24.2 - Prob. 3TQCh. 24.2 - Prob. 4TQCh. 24.2 - Prob. 5TQCh. 24.3 - Prob. 1TQCh. 24.3 - Prob. 2TQ
Ch. 24.3 - Prob. 3TQCh. 24.4 - Prob. 1TQCh. 24.4 - Prob. 2TQCh. 24.5 - Prob. 1TQCh. 24.5 - Prob. 2TQCh. 24.6 - Prob. 1TQCh. 24.6 - Prob. 2TQCh. 24 - Prob. 1RQCh. 24 - Prob. 2RQCh. 24 - Prob. 3RQCh. 24 - Prob. 4RQCh. 24 - Prob. 5RQCh. 24 - Prob. 6RQCh. 24 - Prob. 7RQCh. 24 - Prob. 8RQCh. 24 - Prob. 9RQCh. 24 - Prob. 10RQCh. 24 - Prob. 11RQCh. 24 - Prob. 12RQCh. 24 - Prob. 13RQCh. 24 - Prob. 14RQCh. 24 - Prob. 15RQCh. 24 - Prob. 16RQCh. 24 - Prob. 17RQCh. 24 - Prob. 18RQCh. 24 - Prob. 19RQCh. 24 - Prob. 20RQCh. 24 - Prob. 1TQCh. 24 - Prob. 2TQCh. 24 - Prob. 3TQCh. 24 - Prob. 4TQCh. 24 - Prob. 5TQ
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