Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 13, Problem 2P
Summary Introduction

a.

To determine:

The appearance of chromosome 1 after FISH having genotypes Del1/Del2.

Introduction:

Human chromosome 1 is a large metacentric chromosome. Some of the telomeric regions on the chromosome were barcoded by multicolor banding. Fluorescence In situ Hybridization technique (FISH) is used to label the DNA probes.

Summary Introduction

b.

To determine:

The appearance of chromosome 1 after FISH having genotypes Del1/+.

Introduction:

Multicolor banding is done towards the telomeric end of chromosome 1 using different fluorescent dyes. This technique of banding is called FISH. The banding pattern is unique for different genotypes.

Summary Introduction

c.

To determine:

The appearance of chromosome 1 after FISH having genotypes Inv1/+.

Introduction:

Inversion refers to a type of chromosomal mutation in which a segment of a chromosome gets reversed from one end to the other. Inversion is of two types, paracentric and pericentric inversion. Pericentric inversion includes the centromere, whereas; paracentric inversion does not involve centromere.

Summary Introduction

d.

To determine:

The appearance of chromosome 1 after FISH having genotypes Inv2/+.

Introduction:

Inversion can be classified into two types, paracentric and pericentric inversion. Pericentric inversion includes the centromere, whereas; paracentric inversion does not involve centromere.

Summary Introduction

e.

To determine:

The appearance of chromosome 1 after FISH having genotypes Inv2/Inv2.

Introduction:

The technique of banding the chromosomal region by using different fluorescent dyes is called FISH. The banding pattern is unique for different genotypes.

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Chapter 13 Solutions

Genetics: From Genes to Genomes

Ch. 13 - Genes a and b are 21 m.u. apart when mapped in...Ch. 13 - In the following group of figures, the pink lines...Ch. 13 - Three strains of Drosophila Bravo, X-ray, and...Ch. 13 - Two yeast strains were mated and sporulated...Ch. 13 - Suppose a haploid yeast strain carrying two...Ch. 13 - In the mating between two haploid yeast strains...Ch. 13 - During ascus formation in Neurospora, any...Ch. 13 - In the following figure, black and pink lines...Ch. 13 - In Drosophila, the gene for cinnabar eye color is...Ch. 13 - Semisterility in corn, as seen by unfilled ears...Ch. 13 - A promising biological method for insect control...Ch. 13 - Prob. 23PCh. 13 - a. Among the progeny of a self-fertilized...Ch. 13 - Duchenne muscular dystrophy DMD is caused by a...Ch. 13 - WHIM syndrome is a disease of the immune system...Ch. 13 - Explain how transposable elements can cause the...Ch. 13 - The Drosophila genome normally harbors about 40 P...Ch. 13 - Drosophila P elements were discovered because of a...Ch. 13 - Flies homozygous for mutant alleles of a...Ch. 13 - Fred and Mary have a child named Bob. The genomic...Ch. 13 - Uniparental disomy is a rare phenomenon in which...Ch. 13 - Among adults with Turner syndrome, it has been...Ch. 13 - In Neurospora, his2 mutants require the amino acid...Ch. 13 - Human geneticists interested in the effects of...Ch. 13 - The incidence of Down syndrome will be very high...Ch. 13 - The Drosophila chromosome 4 is extremely small;...Ch. 13 - Down syndrome is usually caused by having a...Ch. 13 - Common red clover, Trifolium pratense, is a...Ch. 13 - The numbers of chromosomes in the somatic cells of...Ch. 13 - Prob. 41PCh. 13 - Somatic cells in organisms of a particular diploid...Ch. 13 - An allotetraploid species has a genome composed of...Ch. 13 - Prob. 44PCh. 13 - Chromosomes normally associate during meiosis I as...Ch. 13 - Using whole-genome sequencing, how could you...Ch. 13 - Prob. 47PCh. 13 - Prob. 48PCh. 13 - Seedless watermelons that you find in the...Ch. 13 - The names of hybrid animals are usually themselves...Ch. 13 - While most animals cannot tolerate polyploidy,...Ch. 13 - What characteristic property of translocations...Ch. 13 - Prob. 53PCh. 13 - In the accompanying figure, the top and bottom...Ch. 13 - Prob. 55PCh. 13 - The accompanying figure shows idiograms of human...Ch. 13 - Prob. 57P
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