Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 13, Problem 4P
For the following types of chromosomal rearrangements, would it theoretically ever be possible to obtain a perfect reversion of the rearrangement? If so, would such revertants be found only rarely, or would they be relatively common?
a. | A deletion of a region including five genes |
b. | A tandem duplication of a region including five genes |
c. | A pericentric inversion |
d. | A Robertsonian translocation |
e. | A mutation caused by a transposable element jumping into a protein-coding exon of a gene |
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
What kind of chromosome rearrangement (shown as ?) is represented below?
a. insertion
b. Pericentric inversion
c. Robersonian translocation
d. Paracentric inversion
e. balanced translocation
Consider the following two wild type chromosomes:
AB•CDEFGH
I•JKLMN
What kind of rearrangement is observed in the mutated chromosomes below?
AB•CLMN
I•JKDEFGH
A.
non-reciprocal translocation
B.
tandem duplication
C.
reciprocal translocation
D.
displaced duplication
E.
deletion
Which of the following is true regarding the presence of a multigene family?
A. Multigene families are produced by any sort of chromosomal rearrangement.
B. Multigene families are produced whenever a transposon is inserted into a gene.
C. Multigene families are produced by all types of mutation, including single base substitutions.
D. Multigene families are produced by some mutations that involve duplication.
Chapter 13 Solutions
Genetics: From Genes to Genomes
Ch. 13 - For each of the terms in the left column, choose...Ch. 13 - Prob. 2PCh. 13 - For each of the following types of chromosomal...Ch. 13 - For the following types of chromosomal...Ch. 13 - One of the X chromosomes in a particular...Ch. 13 - A diploid strain of yeast was made by mating a...Ch. 13 - The two graphs that follow represent genomic...Ch. 13 - A series of chromosomal mutations in Drosophila...Ch. 13 - Indicate which of the four major classes of...Ch. 13 - The recessive, X-linked z1 mutation of the...
Ch. 13 - Genes a and b are 21 m.u. apart when mapped in...Ch. 13 - In the following group of figures, the pink lines...Ch. 13 - Three strains of Drosophila Bravo, X-ray, and...Ch. 13 - Two yeast strains were mated and sporulated...Ch. 13 - Suppose a haploid yeast strain carrying two...Ch. 13 - In the mating between two haploid yeast strains...Ch. 13 - During ascus formation in Neurospora, any...Ch. 13 - In the following figure, black and pink lines...Ch. 13 - In Drosophila, the gene for cinnabar eye color is...Ch. 13 - Semisterility in corn, as seen by unfilled ears...Ch. 13 - A promising biological method for insect control...Ch. 13 - Prob. 23PCh. 13 - a. Among the progeny of a self-fertilized...Ch. 13 - Duchenne muscular dystrophy DMD is caused by a...Ch. 13 - WHIM syndrome is a disease of the immune system...Ch. 13 - Explain how transposable elements can cause the...Ch. 13 - The Drosophila genome normally harbors about 40 P...Ch. 13 - Drosophila P elements were discovered because of a...Ch. 13 - Flies homozygous for mutant alleles of a...Ch. 13 - Fred and Mary have a child named Bob. The genomic...Ch. 13 - Uniparental disomy is a rare phenomenon in which...Ch. 13 - Among adults with Turner syndrome, it has been...Ch. 13 - In Neurospora, his2 mutants require the amino acid...Ch. 13 - Human geneticists interested in the effects of...Ch. 13 - The incidence of Down syndrome will be very high...Ch. 13 - The Drosophila chromosome 4 is extremely small;...Ch. 13 - Down syndrome is usually caused by having a...Ch. 13 - Common red clover, Trifolium pratense, is a...Ch. 13 - The numbers of chromosomes in the somatic cells of...Ch. 13 - Prob. 41PCh. 13 - Somatic cells in organisms of a particular diploid...Ch. 13 - An allotetraploid species has a genome composed of...Ch. 13 - Prob. 44PCh. 13 - Chromosomes normally associate during meiosis I as...Ch. 13 - Using whole-genome sequencing, how could you...Ch. 13 - Prob. 47PCh. 13 - Prob. 48PCh. 13 - Seedless watermelons that you find in the...Ch. 13 - The names of hybrid animals are usually themselves...Ch. 13 - While most animals cannot tolerate polyploidy,...Ch. 13 - What characteristic property of translocations...Ch. 13 - Prob. 53PCh. 13 - In the accompanying figure, the top and bottom...Ch. 13 - Prob. 55PCh. 13 - The accompanying figure shows idiograms of human...Ch. 13 - Prob. 57P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- . For the following types of chromosomal rearrangements,would it theoretically ever be possible to obtain aperfect reversion of the rearrangement? If so, wouldsuch revertants be found only rarely, or would theybe relatively common?a. A deletion of a region including five genesb. A tandem duplication of a region including five genesc. A pericentric inversiond. A Robertsonian translocatione. A mutation caused by a transposable elementjumping into a protein-coding exon of a genearrow_forwardWhich of these chromosomal rearrangements will result in formation of a loop during prophase I if an organism is heterozygous for the chromosomal aberration? Select all correct answers. A.)reciprocal translocation B.)tandem duplication C.)Robertsonian translocation D.)pericentric inversion E.)paracentric inversionarrow_forwardIndicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. a. Semisterility b. Lethality c. Vulnerability to mutation d. Haploinsufficiency e. Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) f. Crossover suppression g. Aneuploidyarrow_forward
- Which type(s) of chromosomal aberrations result from chromosomal breaks on different chromosomes? Assume that a heterozygote for the aberration is viable. Select all correct answers. A.)Robertsonian translocation B.)reciprocal translocation C.)tandem duplication D.)paracentric inversion E.)pericentric inversion F.)large deletionarrow_forwardDefine the following terms: a. single nucleotide polymorphism b. nonsense mutation c. indel d. inversion e. translocationarrow_forwardWhich type(s) of chromosomal aberrations is/are likely to cause semisterility? Select all correct answers. A.)reciprocal translocations B.)deletions C.)inversions D.) duplicationsarrow_forward
- A recent estimate of the rate of base substitutions atSNP loci is about 1 × 10−8 per nucleotide pair pergamete.a. Based on this estimate, about how many de novomutations (that is, mutations not found in the genomes of your parents) are present in your own genome?b. Where and when did these de novo mutations inyour genome most likely occur?c. It has been calculated that each sperm made in a25-year-old man is the result on average of about300 rounds of cell division, starting with the firstmitotic division of the male zygote. In contrast,each mature oocyte found in a 5-month-old femalehuman fetus is the result of about 25 rounds of division, starting with the first mitotic division of thefemale zygote. What bearing do these calculations have on the estimate of the rate of base substitutions in humans, and on your answer to part (b)?arrow_forwardDefine the following terms:a. nonreplicative transpositionb. replicative transpositionc. composite transposond. retrotransposone. insertional elementarrow_forwardConsider the following two wild type chromosomes: AB•CDEFGH I•JKLMN What kind of rearrangement is observed in the mutated chromosomes below? AB•CDEKLMNFGH I•J A. reciprocal translocation B. non-reciprocal translocation C. displaced duplication D. pericentric inversion E. paracentric inversionarrow_forward
- Define the following terms: a. transposition b. DNA glycosylase c. apurinic site d. apyrimidinic site e. mismatch repairarrow_forwardWith regard to gene duplications, which of the following statement(s) is/are correct?a. Gene duplications may be caused by nonallelic homologousrecombination.b. Large gene duplications are more likely to be harmful thansmaller ones.c. Gene duplications are responsible for creating gene familiesthat encode proteins with similar and specialized functions.d. All of the above statements are correct.arrow_forwardA pair of paralogous repeats, A and B, have 96% sequence similarity and therefore can promote non-allelic homologous recombination (NAHR). They exist in four possible arrangements in a genome, illustrated below as arrangements 1 – 4. What is the result of NAHR between repeats A and B in arrangement 1? A.Translocation between chromosomes 1 and 2 resulting in monocentric chromosomes B.Deletion or duplication of the region between A and B C.Translocation between chromosomes 1 and 2 resulting in acentric and dicentric chromosomes D.Inversion of the region between A and Barrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY