Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 13, Problem 3P
For each of the following types of chromosomal aberrations, tell: (i) whether the chromosomes of an organism heterozygous for the aberration will form any type of loop during prophase I of meiosis; (ii) whether a chromosomal bridge can be formed during anaphase I in a heterozygote, and if so, under what conditions; (iii) whether an acentric fragment can be formed during anaphase I in a heterozygote, and if so, under what conditions; (iv) whether the aberration can suppress meiotic recombination; and (v) whether the two chromosomal breaks responsible for the aberration occur on the same side or on opposite sides of a single centromere, or if the two breaks occur on different chromosomes.
| a. | Reciprocal translocation |
| b. | Paracentric inversion |
| c. | Small tandem duplication |
| d. | Robertsonian translocation |
| e. | Pericentric Inversion |
| f. | Large deletion |
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For each of the following types of chromosomalaberrations, tell: (i) whether the chromosomes of anorganism heterozygous for the aberration will formany type of loop during prophase I of meiosis;(ii) whether a chromosomal bridge can be formedduring anaphase I in a heterozygote, and if so, underwhat conditions; (iii) whether an acentric fragmentcan be formed during anaphase I in a heterozygote,and if so, under what conditions; (iv) whether theaberration can suppress meiotic recombination; and(v) whether the two chromosomal breaks responsible for the aberration occur on the same side or on opposite sides of a single centromere, or if the two breaksoccur on different chromosomes.a. Reciprocal translocationb. Paracentric inversionc. Small tandem duplicationd. Robertsonian translocatione. Pericentric inversionf. Large deletion
Consider the following two meiocytes in metaphase I, with crossover positions as indicated for cell A. Solid black lines indicate spindle microtubules. Assume blue chromosomes represents paternal chromosomes and green maternal chromosomes.
i) How many chromosomes and chromatids were present in cell A during the G1 phase? Please clearly specify chromosomes and chromatids in your answer. ii) For cell A, list all the gametes that will be produced from this cell. Give the alleles of each gamete contained within a set of brackets. You may ignore independent assortment.iii) For cell B, list all the gametes that will be produced from this cell given crossing over. Give the alleles of each gamete contained within a set of brackets. You may assume that no crossing over would take place.
An individual heterozygous for a reciprocal translocation possesses the following chromosomes:
A B • C D E F G
A B • C D V W X
R S • T U E F G
R S • T U V W X
Q. Draw the pairing arrangement of these chromosomes in prophase I of meiosis.
Chapter 13 Solutions
Genetics: From Genes to Genomes
Ch. 13 - For each of the terms in the left column, choose...Ch. 13 - Prob. 2PCh. 13 - For each of the following types of chromosomal...Ch. 13 - For the following types of chromosomal...Ch. 13 - One of the X chromosomes in a particular...Ch. 13 - A diploid strain of yeast was made by mating a...Ch. 13 - The two graphs that follow represent genomic...Ch. 13 - A series of chromosomal mutations in Drosophila...Ch. 13 - Indicate which of the four major classes of...Ch. 13 - The recessive, X-linked z1 mutation of the...
Ch. 13 - Genes a and b are 21 m.u. apart when mapped in...Ch. 13 - In the following group of figures, the pink lines...Ch. 13 - Three strains of Drosophila Bravo, X-ray, and...Ch. 13 - Two yeast strains were mated and sporulated...Ch. 13 - Suppose a haploid yeast strain carrying two...Ch. 13 - In the mating between two haploid yeast strains...Ch. 13 - During ascus formation in Neurospora, any...Ch. 13 - In the following figure, black and pink lines...Ch. 13 - In Drosophila, the gene for cinnabar eye color is...Ch. 13 - Semisterility in corn, as seen by unfilled ears...Ch. 13 - A promising biological method for insect control...Ch. 13 - Prob. 23PCh. 13 - a. Among the progeny of a self-fertilized...Ch. 13 - Duchenne muscular dystrophy DMD is caused by a...Ch. 13 - WHIM syndrome is a disease of the immune system...Ch. 13 - Explain how transposable elements can cause the...Ch. 13 - The Drosophila genome normally harbors about 40 P...Ch. 13 - Drosophila P elements were discovered because of a...Ch. 13 - Flies homozygous for mutant alleles of a...Ch. 13 - Fred and Mary have a child named Bob. The genomic...Ch. 13 - Uniparental disomy is a rare phenomenon in which...Ch. 13 - Among adults with Turner syndrome, it has been...Ch. 13 - In Neurospora, his2 mutants require the amino acid...Ch. 13 - Human geneticists interested in the effects of...Ch. 13 - The incidence of Down syndrome will be very high...Ch. 13 - The Drosophila chromosome 4 is extremely small;...Ch. 13 - Down syndrome is usually caused by having a...Ch. 13 - Common red clover, Trifolium pratense, is a...Ch. 13 - The numbers of chromosomes in the somatic cells of...Ch. 13 - Prob. 41PCh. 13 - Somatic cells in organisms of a particular diploid...Ch. 13 - An allotetraploid species has a genome composed of...Ch. 13 - Prob. 44PCh. 13 - Chromosomes normally associate during meiosis I as...Ch. 13 - Using whole-genome sequencing, how could you...Ch. 13 - Prob. 47PCh. 13 - Prob. 48PCh. 13 - Seedless watermelons that you find in the...Ch. 13 - The names of hybrid animals are usually themselves...Ch. 13 - While most animals cannot tolerate polyploidy,...Ch. 13 - What characteristic property of translocations...Ch. 13 - Prob. 53PCh. 13 - In the accompanying figure, the top and bottom...Ch. 13 - Prob. 55PCh. 13 - The accompanying figure shows idiograms of human...Ch. 13 - Prob. 57P
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