Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 9, Problem 31CONQ
Summary Introduction
To analyze:
The length of a 100 million base pair long chromosome.
Introduction:
Deoxyribonucleic acid (DNA) acts as a genetic material. It is present in most cells. The DNA present in a nucleus is in a highly compressed form (chromosomes) in order to fit the complete length inside a small organelle.
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A medium-sized human chromosome contains about 100 millionbp. If the DNA were stretched out in a linear manner, how longwould it be?
Suppose that E. coli synthesizes DNA at a rate of 100,000 nucleotides per minute and takes 40 minutes to replicate its chromosome. (a) How many base pairs are present in the entire E. coli chromosome? (b) What is the physical length of the chromosome in its helical configuration—that is, what is the circumference of the chromosome if it were opened into a circle?
The human genome contains about 3 billion base pairs. During the first cell division after fertilization of a human embryo, S phase is approximately three hours long. Assuming an average DNA polymerase rate of 50 nucleotides/second over the entire S phase, what is the minimum number oforigins of replication you would expect to find in the human genome? Show your solution.
Chapter 9 Solutions
Genetics: Analysis and Principles
Ch. 9.1 - In the experiment of Avery, McLeod, and McCarty,...Ch. 9.1 - In the Hershey and Chase experiment involving T2...Ch. 9.2 - Going from simple to complex, which of the...Ch. 9.3 - Which of the following could be the components of...Ch. 9.3 - Prob. 2COMQCh. 9.4 - Prob. 1COMQCh. 9.5 - Prob. 1COMQCh. 9.5 - Prob. 2COMQCh. 9.6 - 1. Which of the following is not a feature of the...Ch. 9.6 - 2. A groove in the DNA refers to
a. the...
Ch. 9.6 - Prob. 3COMQCh. 9.7 - 1. A double-stranded region of RNA
a. forms a...Ch. 9 - 1. What is the meaning of the term genetic...Ch. 9 - Prob. 2CONQCh. 9 - 3. Look up the meaning of the word transformation...Ch. 9 - Prob. 4CONQCh. 9 - 5. Draw the structures of guanine, guanosine, and...Ch. 9 - Prob. 6CONQCh. 9 - 7. Describe how bases interact with each other in...Ch. 9 - Prob. 8CONQCh. 9 - 9. What is meant by the term DNA sequence?
Ch. 9 - Make a side-by-side drawing of two DNA helices:...Ch. 9 - 11. Discuss the differences in the structural...Ch. 9 - What part(s) of a nucleotide (namely, phosphate,...Ch. 9 - List the structural differences between DNA and...Ch. 9 - Draw the structure of deoxyribose and number the...Ch. 9 - Write a sequence of an RNA molecule that could...Ch. 9 - Compare the structural features of a...Ch. 9 - Which of the following DNA double helices would be...Ch. 9 - What structural feature allows DNA to store...Ch. 9 - Prob. 19CONQCh. 9 - Prob. 20CONQCh. 9 - Prob. 21CONQCh. 9 - 22. On further analysis of the DNA described in...Ch. 9 - Prob. 23CONQCh. 9 - Prob. 24CONQCh. 9 - In what ways are the structures of an helix in a...Ch. 9 - Prob. 26CONQCh. 9 - Prob. 27CONQCh. 9 - 28. What chemical group (phosphate group, hydroxyl...Ch. 9 - The base composition of an RNA virus was analyzed...Ch. 9 - Prob. 30CONQCh. 9 - Prob. 31CONQCh. 9 - Prob. 32CONQCh. 9 - Prob. 33CONQCh. 9 - As described in Chapter 15, the methylation of...Ch. 9 - 35. An RNA molecule has the following sequence:...Ch. 9 - 1. Genetic material acts as a blueprint for an...Ch. 9 - 2. With regard to the experiment described in...Ch. 9 - Prob. 3EQCh. 9 - Prob. 4EQCh. 9 - 5. With regard to Chargaff’s experiment described...Ch. 9 - 6. Gierer and Schramm exposed plant tissue to...Ch. 9 - 1. Try to propose structures for a genetic...Ch. 9 - Prob. 2QSDC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- If the DNA of chromosome 1 is fully extended, it will exceed the diameter of the nucleus of a cell by about 15,000 times. Therefore, discuss how DNA is packaged into the cell.arrow_forwardEach cell of the human body contains 46 chromosomes. How many DNA molecules does this statement represent? How many different types of DNA molecules does it represent?arrow_forwardA double-stranded DNA molecule is 1 cm long, and the percentage of adenine is 15%. How many cytosines does this DNA molecule contain?arrow_forward
- The human genome contains 3 billion nucleotides arranged in a vast array of sequences. What is the minimum length of a DNA sequence that will, in all probability, appear only once in the human genome? You need consider only one strand and may assume that all four nucleotides have the same probability of appearance.arrow_forwardHow many adenine bases are there if there are eight thousand cytosine bases in a fifteen thousand bp DNA?arrow_forwardLet’s assume the linker region of DNA averages 54 bp in length. How many molecules of H2A would you expect to find in a DNA sample that is 46,000 bp in length?arrow_forward
- The average human chromosome contains about 1 x 108 bp of DNA.(a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much doessuch a chromosome weigh (in grams)?(b) If the DNA were extended, how long would it be?(c) An actual chromosome is about 5 mm long. What is the approximatecompaction ratio?(d) You have about 4 x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun isabout 1.5 x 108 km.arrow_forwardAssuming that the DNA codes for 20 amino acids, where each amino acid is coded by 3 nucleotides each. What is the length of the DNA if 1 turn made up of 10 nucleotide base pairs measures 34A?arrow_forwardIf the DNA of one human cell is stretched out, it would be almost 6 feet long and contain over three billion base pairs. How does all this fit into the nucleus of one cell?arrow_forward
- The telomeres of a linear chromosome are made of identical directly repeated DNA sequences. How does the enzyme telomerase generate these DNA repeats?arrow_forwardBack in the 1950s, the techniques for isolating DNA from cells all yielded molecules of about 10,000 to 20,000 base pairs. We now know that the DNA molecules in all cells are much longer. Why do you suppose such short pieces were originally isolated? Explain your answer in 1-2 sentences.arrow_forwardA diploid human cell contains approximately 6.4 billion base pairs of DNA. Assuming that the linker DNA encompasses 35 bp, how many nucleosomes are present in such a cell? Use two significant figures. How many histone proteins are complexed with this DNA? use two significant figures.arrow_forward
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