The average human chromosome contains about 1 x 108 bp of DNA.(a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much doessuch a chromosome weigh (in grams)?(b) If the DNA were extended, how long would it be?(c) An actual chromosome is about 5 mm long. What is the approximatecompaction ratio?(d) You have about 4 x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun isabout 1.5 x 108 km.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The average human chromosome contains about 1 x 108 bp of DNA.
(a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much does
such a chromosome weigh (in grams)?
(b) If the DNA were extended, how long would it be?
(c) An actual chromosome is about 5 mm long. What is the approximate
compaction ratio?
(d) You have about 4 x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun is
about 1.5 x 108 km.
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