The explanation that helps in understanding the reason that inserted amino acids do not correspond to normal protein sequence. Introduction: Amino acids are vital molecules that produce proteins. The process by which mRNA is transformed into amino acids is known as translation. The amino acids join together with the help of polypeptide bonds to form proteins. A scientist observed that a natural enzyme is composed of 227 amino acids. However, the mutant form of this enzyme contains 312 amino acids. This indicates that the mutant form has 85 extra amino acids.

Question

Want to see the full answer?

Answer 1

Question

Chapter 8, Problem 23P

Summary Introduction

To describe:

The explanation that helps in understanding the reason that inserted amino acids do not correspond to normal protein sequence.

Introduction:

Amino acids are vital molecules that produce proteins. The process by which mRNA is transformed into amino acids is known as translation. The amino acids join together with the help of polypeptide bonds to form proteins. A scientist observed that a natural enzyme is composed of 227 amino acids. However, the mutant form of this enzyme contains 312 amino acids. This indicates that the mutant form has 85 extra amino acids.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

In the image below, the blue squiggly line represents a folded protein. There are two particular amino acids that are colored red and black in the protein. The structure of each of these two specific amino acids is shown in the indicated box. A mutation occurs in the gene that encodes the protein illustrated above. The result of this mutation is that one of the amino acids above is substituted with another. Specifically, the amino acid whose structure is shaded red above (the one on the left in the illustration) is replaced by the amino acid shown below. Use this information to answer the two questions that follow. Please answer these questions. 1. Based on this description, indicate which type of mutation occurred: missense, nonsense, silent, or indel 2. How would this mutation affect this protein's structure and function? Explain in 2-4 sentences. Be specific, and be sure to include details of these specific amino acids in your response. (I'm giving you the…

E. How many nucleotides would be required to generate a polypeptide that is 15 amino acids long? This requires knowing how many nucleotides of DNA code for one amino acid. F. Assuming that there are between 20,000-25,000 genes in the human genome, do you think there are 1) fewer, 2) approximately the same number, or 3) more proteins in the human genome? Explain your answer.

Suppose that there is an unknown protein that underwent Edman sequencing method. From N- terminal determination, a biochemist found out that there are two N-terminal amino acid residues, V and G. What is the original sequence of the protein given the following peptide fragments: after digestion with Chymotrypsin: G-L-S-R-G-M-w V-A-L-F Q-L-Y L-R-V-W G-M-V-E-A-D-I-P K-S-P-E-M-T-W R-M-A-S-E-K-P-G-H after digestion with Trypsin: P-G-H V-W-G-M-V-E-A-D-I-P M-A-S-E-K G-M-W-Q-L-Y-L-R S-P-E-M-T-W-R G-L-S-R V-A-L-F-K after digestion with Cyanogen Bromide: T-W-R-M W-Q-L-Y-L-R-V-W-G-M V-E-A-D-I-P A-S-E-K-P-G-H V-A-L-F-K-S-P-E-M G-L-S-R-G-M