a. To determine: The elements that occur in the gene primary transcript or mRNA. Introduction: The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

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Answer 1

Question

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

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The following RNA sequence represents a small messenger which can be translated in a prokaryotic cell: 5'-ACGAAUGCACAGUAAAACUGGCUAGCGUAGGCUGA-3 Assume that the messenger RNA is translated in the cell, using the correct machinery and signals required for accurate protein synthesis. Using this RNA sequence and the Genetic Code Dictionary (see your textbook for the dictionary), solve the following problems A. Write the sequence of a protein that would be translated from this mRNA, using the appropriate stop and start signals, and indicating the correct termini of the protein product. B. Suppose that the underlined A in the sequence is changed to a U. Write the expected protein product of this mRNA.

Many clinically relevant mitochondrial diseases are caused by mutations in mitochondrial genes affecting tRNAs. For example, one form of MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) is caused by a point mutation in the gene encoding the mitochondrial tRNA whose anticodon recognizes the codons 5' UUA and 5' UUG. The mutation makes the aminoacylation of this tRNA inefficient. a. The rate of synthesis of most mitochondrial proteins is either unaffected or slightly decreased in MELAS cells, but one mitochondrial protein called NAD6 is synthesized at only 10% of the normal rate. How is it possible that the translation of this single mitochondrial protein might be affected specifically?

Consider the mechanism of the enzyme RNase:  What would happen to the Km (i.e., would it increase, decrease, or stay the same) if the his12 was mutated to a lysine? Explain.  What would happen to the Kcat (i.e., would it increase, decrease, or stay the same) if the his12 was mutated to a valine? Explain.

Answer 2

Question

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Expert Solution & Answer

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Answer 3

Question

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Expert Solution & Answer

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Answer 4

Question

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Answer 6

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Answer 7

Chapter 8, Problem 35P

Summary Introduction

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Answer 8

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Answer 9

Summary Introduction

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

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Answer 13

Ch. 8 - For each of the terms in the left column, choose...Ch. 8 - Match the hypothesis from the left column to the...Ch. 8 - How would the artificial mRNA 5GUGUGUGU . . . 3 be...Ch. 8 - An example of a portion of the T4 rIIB gene in...Ch. 8 - Consider Crick and Brenners experiments in Fig....Ch. 8 - The HbSsickle-cell allele of the human -globin...Ch. 8 - The following diagram describes the mRNA sequence...Ch. 8 - The amino acid sequence of part of a protein has...Ch. 8 - The results shown in Fig. 8.5 may have struck you...Ch. 8 - Identify all the amino acid-specifying codons in...

a. To determine: The elements that occur in the gene primary transcript or mRNA. Introduction: The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Solution Summary: The author explains that the RNA polymerase recognizes both the promoter and the transcription terminator in the primary mRNA transcript.

Concept explainers

Videos

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Want to see the full answer?

Chapter 8 Solutions

a. To determine: The elements that occur in the gene primary transcript or mRNA. Introduction: The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

Solution Summary: The author explains that the RNA polymerase recognizes both the promoter and the transcription terminator in the primary mRNA transcript.

Concept explainers

Videos

a. To determine: The elements that occur in the gene primary transcript or mRNA. Introduction: The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

b. To determine: The elements found in the first exon, intron, and the second axon. Introduction: The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.

Want to see the full answer?

Chapter 8 Solutions

a.

To determine:

The elements that occur in the gene primary transcript or mRNA.

Introduction:

The mRNA also referred to as the messenger RNA are molecules that are responsible for the transmission of genetic information from the DNA to the ribosomes.

b.

To determine:

The elements found in the first exon, intron, and the second axon.

Introduction:

The messenger RNA structure consists of introns and exons in the case of eukaryotes. The introns are the non-coding regions, whereas the exons are the coding regions.