Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 43, Problem 2IQ
Summary Introduction
To complete: The table that summarizes the functions of the cells and chemicals of the innate defense mechanisms of mammals.
Introduction: The immune system protects the body from the invading pathogenic organisms. The immune system is classified into two types, namely the innate immune system and adaptive immune system. The innate immune system is the defense mechanism found already from the birth whereas the adaptive immune system is acquired at the later stages of life when exposed to antigens. The white blood cells that involve in innate immunity are natural killer cells, mast cells, eosinophils, basophils, macrophages, neutrophils, and dendritic cells.
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Toll-like receptors represent an ancient pathogen-recognition system. The first pattern recognition receptor (PRR) important in innate immune responses was discovered in the fruit fly Drosophila melanogaster. Stimulation of this receptor, called Toll, induces:
The synthesis of prostaglandins and leukotrienes
The inflammatory response in Drosophila hemolymph vessels
The production of antimicrobial peptides
The recruitment of phagocytic cells to the site of infection
The activation of Drosophila complement
Explain seven innate (nonspecific) defense mechanisms.
List the various types of Human defense mechanisms (Specific and Non-specific) WITH examples
for each.
Chapter 43 Solutions
Study Guide for Campbell Biology
Ch. 43 - Briefly describe the insect defense system against...Ch. 43 - Prob. 2IQCh. 43 - Prob. 3IQCh. 43 - Prob. 4IQCh. 43 - Prob. 5IQCh. 43 - Prob. 6IQCh. 43 - Prob. 7IQCh. 43 - Prob. 8IQCh. 43 - Prob. 9IQCh. 43 - Prob. 1SYK
Ch. 43 - Prob. 2SYKCh. 43 - Although innate and adaptive immunity were...Ch. 43 - Prob. 1TYKCh. 43 - Prob. 2TYKCh. 43 - Prob. 3TYKCh. 43 - The process of clonal selection accounts for a....Ch. 43 - Prob. 5TYKCh. 43 - Which of the following destroys a target cell by...Ch. 43 - Prob. 7TYKCh. 43 - Prob. 8TYKCh. 43 - Prob. 9TYKCh. 43 - Prob. 10TYKCh. 43 - Prob. 11TYKCh. 43 - Prob. 12TYKCh. 43 - Prob. 13TYKCh. 43 - Prob. 14TYKCh. 43 - Prob. 15TYKCh. 43 - Prob. 16TYKCh. 43 - Prob. 17TYKCh. 43 - What is the key advantage to the use of monoclonal...Ch. 43 - Prob. 19TYKCh. 43 - Prob. 20TYKCh. 43 - Prob. 21TYKCh. 43 - From which of the following conditions would an...
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- The classic inflammatory response (heat, swelling, redness, pain) reflects the communication of innate and adaptive defenses. Which of the following is not correct about this response? Group of answer choices Non-cytopathic viruses stimulate the inflammatory response Adjuvants stimulate inflammation and therefore a good antibody response Dendritic cells link the innate and adaptive responses Tumor necrosis factor alpha is a major inducer of inflammation Increased blood flow is one result of inflammationarrow_forwardThe effector mechanisms that are recruited to clear an infection depend on the infectious agent. In addition to producing distinct innate responses locally at the site of infection, the different cytokines produced during type I, type 2, or type 3 immune responses also induce distinct adaptive immune responses that are tailored to the eradication of the three different classes of pathogens. One example is the production of different classes of antibodies during type I, type 2, or type 3 responses. Which step during the induction of the adaptive immune response is the key to generating and coordinating the three different immune modules?arrow_forwardExplain the innate defense systemarrow_forward
- Which of the following is true about innate immune system? Check all that apply. Rig-I-like receptors have the advantage of recognizing viruses by interacting with their spike proteins TLR signaling includes NF-kB pathways to induce synthesis of proinflammatory cytokines TLR binds to dsDNA or ssRNA to induce interferon gene expression PRR induced secretion of proinflammatory cytokines and chemokines have local and systemic effects PRR induces innate immunity; phagocytosis, inflammation, type I interferon production, and regulate adaptive immunity; DC maturation, costimulatory molecules, type I interferonarrow_forwardCompare and contrast the receptors used by the innate vs. adaptive immune systems to recognize "non-self." Consider the cells that express them, the receptor structures/diversity of ligands, outcomes of the associated signaling pathways, etc.arrow_forwardExplain the adaptive defense systemarrow_forward
- What distinguishes the innate defense system from the adaptive defense system.arrow_forwardWhat part of defense would likely be affected if the pathogen contained a mutation in it's pathogen-associated molecular patterns (PAMPs)? the pathogen would secrete greater amounts of toxins. the pathogen might not be recognized by the host. the pathogen would be easily recognized by the host's TLRs. the pathogen would not be able to penetrate the host's physical barriers.arrow_forwardWhich of the following is a component of the first line of defense in the innate defense system? T cell activation phagocyte and natural killer cell activation secretion of sweat and sebum onto the epidermis all the above a and barrow_forward
- An adaptive immune response underlying coeliac disease pathogenesis involves: a) Production of Th1 (T helper cell 1 type) cytokines that act to promote the production of antibodies to gluten peptides b) Production of anti-gliadin and anti-tissue transglutaminase antibodies via TH2 cytokines c) Conversion of glutamate to glutamine by deamination d) The early recognition of gluten peptides via pattern recognition receptors on epithelial cells and the subsequent release of Interleukin 15arrow_forwardWhen surface barriers protecting the body are breached, the second line of defense (of the innate immune system) is activated. These internal defenses include inflammation and phagocytosis amongst other quick responses. Briefly explain acute inflammation in terms of vascular and cellular events. Use your understanding of blood vessels (smooth muscle and endothelial cells), chemical signalling and the interstitial space to help explain the four signs of inflammation - heat, redness, pain and swelling.arrow_forwardThe "Open Window" Theory of exercise and vulnerability to illness is based on all of the following observations, except: Group of answer choices Decreased Natural Killer Cell numbers and activity Decreased nasal and salivary IgA Increased cytokines Increased T-cell numbers and functionarrow_forward
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