Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 43, Problem 17TYK
Summary Introduction
Introduction: T lymphocytes are also known as T-cells, which are primarily produced in the bone marrow. It is then transported to the thymus where the maturation and multiplication of T-cells take place. It is divided into three types based on its surface receptor. They are helper T cells, cytotoxic T cells, and regulatory T cells. The matured T cells are passed to the tissues of the lymph nodes where it gets activated upon entering of the pathogen.
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The following are steps in the cell-mediated inflammatory response. Put them in the correct order.
1. Activated macrophage cells release cytokines.
2. Antigen is engulfed and presented by a macrophage cell w/MHC II complex.
3. The TH1 cell's CD4 protein binds to the MHC II complex.
4. Phagocytosis and inflammation occur.
5. Th1 secrete TNF-alpha and other cytokines which activates the macrophage.
A.
3, 4, 1, 2,5
В.
2, 3, 4, 5, 1
C.
3,5, 4, 1, 2
D.
2,3,5, 1, 4
The following events elicit an antibody response to
a T-dependent antigen (Ag). Put them in order and
indicate which one would happen third (of the five
answers as shown, not necessarily number 3 on a
lecture slide or text diagram).
O
Ag-presenting cell displays Ag fragments
next to self (MHC) molecule on its
surface
Helper T cell (TH) activates an appropriate B
cell
Helper T cell (TH) specific for the Ag binds to
MHC-Ag complex
B cell differentiates into a plasma cell;
secretes antibodies specific for the Ag
Ag-presenting cell phagocytizes Ag-carrying
microbe
Place each events number listed below on the correct part of the “stages ofillness” graph (picture attached) to demonstrate the relationship between your body’s immuneresponse and your symptoms.
Event Numbers:
1. The B cell clones itself into many plasma cells that are producing tons ofantibodies specific to the antigen. Memory B cells form.2. Plasma cells stop producing antibodies and memory B cells remain, ready foranother exposure to the antigens3. Antibody titre begins to decline4. The helper T-cell docks with a B cell shows the antigen to the B cell5. The antigen is engulfed by a macrophage and is present to a helper T cell
Chapter 43 Solutions
Study Guide for Campbell Biology
Ch. 43 - Briefly describe the insect defense system against...Ch. 43 - Prob. 2IQCh. 43 - Prob. 3IQCh. 43 - Prob. 4IQCh. 43 - Prob. 5IQCh. 43 - Prob. 6IQCh. 43 - Prob. 7IQCh. 43 - Prob. 8IQCh. 43 - Prob. 9IQCh. 43 - Prob. 1SYK
Ch. 43 - Prob. 2SYKCh. 43 - Although innate and adaptive immunity were...Ch. 43 - Prob. 1TYKCh. 43 - Prob. 2TYKCh. 43 - Prob. 3TYKCh. 43 - The process of clonal selection accounts for a....Ch. 43 - Prob. 5TYKCh. 43 - Which of the following destroys a target cell by...Ch. 43 - Prob. 7TYKCh. 43 - Prob. 8TYKCh. 43 - Prob. 9TYKCh. 43 - Prob. 10TYKCh. 43 - Prob. 11TYKCh. 43 - Prob. 12TYKCh. 43 - Prob. 13TYKCh. 43 - Prob. 14TYKCh. 43 - Prob. 15TYKCh. 43 - Prob. 16TYKCh. 43 - Prob. 17TYKCh. 43 - What is the key advantage to the use of monoclonal...Ch. 43 - Prob. 19TYKCh. 43 - Prob. 20TYKCh. 43 - Prob. 21TYKCh. 43 - From which of the following conditions would an...
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- Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b. fever f. complement activation c. histamines g. presenting antigen d. cytokines h. all take partarrow_forwardWhich of the following statements pertain to this cell. This cell is a precursor to a cell which: 1. is an antigen-presenting cell 2. demonstrates MHC I molecules 3. demonstrates MHC II molecules 4. demonstrates CD4 molecules 5. is capable of synthesizing and releasing perforin and granzymes Choose from the following: (A) 1, 2, and 3 (B) 2 and 3 only (C) 3 and 4 only (D) 1 and 3 (E) 1, 4, and 5arrow_forwardThe labels describe either a primary or secondary immune response. Drop each label into the appropriate box. Follows second and subsequent encounters with antigen Plasma antibody concentration. First exposure O Primary response IgM made first, then IgG Measurable antibody concentration in 5-10 days 10 20 Secondary response Antibodies produced for several weeks Measurable antibody concentration in 1-2 days 30 Follows first encounter with antigen Memory cells involved Subsequent exposure(s) 40 0 Days after exposure to antigen 10 Only IgG produced 20 30 40arrow_forward
- Which of the following statements is NOT correct? Group of answer choices -Natural killer cells are cytolytic lymphocytes that mediate ADCC -Neutrophils carry out phagocytosis of C3b-tagged particles -Macrophages carry out phagocytosis of C3b-tagged particles -Mast cells produce granules containing the cytotoxin perforin -B lymphocytes express a receptor for complement proteinsarrow_forwardGive a brief overview about the components of both innate and adaptive immunity. In addition to this overview, then compare and contrast innate vs adaptive immunity. Include at least 3 similarities (compare) and 3 differences (contrast)NOT A GRADED ASSIarrow_forwardWhich two events are required to activate a cytotoxic T cell? There is more than one answer. O Class II MHC molecules present extracellular antigen for binding on a complementary cytotoxic T cell receptor. O IL-4 is released by a TH1 cell to be bound by a cytotoxic T cell. O Class I MHC molecules presents intracellular antigen for binding on a complementary cytotoxic T cell receptor O IL-2 is released by a TH1 cell to be bound by a cytotoxic T cell.arrow_forward
- 1. When encountering antigen, describe the mechanism of antigen presentation by B cells. 2. Compare / contrast the advantages and disadvantages of active immunity with passive immunity. 3. Does antibody directly destroy a microbe? EXPLAIN. 4. Use the following terms to construct a coherent mechanism for cell mediated immunity: Interleukin, perforin, CD4 cells, CD8 cells, dendritic cells, MHC class I and class II 5. Upon invasion by a microbial antigen with multiple epitopes (antigenic determinants), What makes clonal selection for T cells and B cells relevant? 6. Why have different classes of antibodies (i.e. IgD, IgE)? 7. Why is the primary and secondary responses to antigen important for the host and for clinical diagnosis? 8. Are all adaptive immune responses the same? EXPLAIN.arrow_forwardMatch each lettered term with the most closely related description. a. cytotoxic T cells Stimulated by the release of cytokines from macrophages, helper T cells, and interferons, b. viruses The race is on: с. В сеlls 15 14 d. antibodies try to replicate before the immune system can mount a response. Two have already taken over cells in the body. quickly recognize the viruses as a foreign threat. They begin destroying viruses by engulfing them. e. helper T cells join the attack on virus- infected cells. They also fight cancer cells. f. macrophages g. natural killer (NK) cells h. regulatory T cells eieg ucl bris ah lo oolom i. memory T cells and B cells neo alled 18 alloo omeslo ofni ola 19 17 are Y-shaped proteins designed specifically to recognize a particular viral mature into plasma cells, which in turn produce Y-shaped proteins. ebie hel ert beer honelni vood avtne er (the battle managers of the immune system) emit sig- nals to other lymphocytes to join the attack. oeonetelagn or…arrow_forwardb) Figure 14 shows a part of acquired immune response. Pathogen P Antigen fragments MHC Antigen гесeptor. CD4 Helper T cell Activated helper T cell Figure 14 i) Describe the above process. II) Why do O and P have different pathways for antigen processing although the same antigen is identified? iii) What are the effects on P when activated helper T cell releases Q7arrow_forward
- TABLE 6 | Correlation between immune markers and age. Marker NCI PAN LCI LP NK activity (lysis %) R Spearman -0.406 -0.305 -0.239 -0.204 -0.016 Р 0.004 0.035 0.101 0.165 0.913 NCI, Neutrophil Chemotaxis Index; PAN, phagocytic activity of neutrophils; LCI, Lymphocyte Chemotaxis Index; LP, lymphocyte proliferation; NK, natural killer. p is the associated value to the corresponding statistical test.arrow_forwardB lymphocytes require which of the following to become activated and to form plasma cells? 1. recognition and binding of an antigen to the B cell receptor 2. presentation of antigen fragments on the B cell surface by MHC I molecules 3. binding of the B cell to an activated T helper cell Choose one from the following: (A) 1 and 2 (B) 1 and 3 (C) 2 and 3 (D) 1,2 and 3arrow_forwardCompare and contrast humoral and cell-mediated immunity. Write three differences and two similarities in terms of function, purpose, types of cells involved, or mechanism. You may write in paragraph form or use a chart/diagram (e'g' Venn diagram) .arrow_forward
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