Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 43, Problem 16TYK
Summary Introduction
The immune system of the human is divided into two types namely innate immunity and adaptive immunity. The innate immunity is the defense that occurs at the time of birth itself. However, the adaptive immunity is acquired by humans in their lifetime when they are exposed to various infections. The adaptive immunity is of two types, namely cell-mediated immunity and humoral immunity. The adaptive immunity involves cells like phagocytes, antigen-specific cytotoxic T lymphocytes, and dendritic cells.
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Which of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells?
a. Macrophages and B cells do not express MHC class II molecules until they are activated.
b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection.
c. Dendritic cells express higher levels of CTLA4.
d. Macrophages and B cells do not process antigen.
e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.
Explain why each choice (a-d) is correct or incorrect.
Which statement is true about T cells?
a. They usually directly recognize antigens, which then activates a subpopulation of killer cells
b. Their proliferation is enhanced by interleukins 1 and 2.
c. Once activated, they cannot secrete cytokines.
d. They will develop into cytotoxic T cells if antigen is complexed with class II MHC proteins.
A number of minor cancerous cells and infected viruses, such as Epstein Barr (EBV), are able to go undetected by cytotoxic T cell degradation by what possible mechanism?
a. the production of normal class I MHC molecule
b. helper T cell activation
c. the deactivation of the complement system
d. tumor antigen expression
e. the production of the class II major histocompatability (MHC) moledule
Chapter 43 Solutions
Study Guide for Campbell Biology
Ch. 43 - Briefly describe the insect defense system against...Ch. 43 - Prob. 2IQCh. 43 - Prob. 3IQCh. 43 - Prob. 4IQCh. 43 - Prob. 5IQCh. 43 - Prob. 6IQCh. 43 - Prob. 7IQCh. 43 - Prob. 8IQCh. 43 - Prob. 9IQCh. 43 - Prob. 1SYK
Ch. 43 - Prob. 2SYKCh. 43 - Although innate and adaptive immunity were...Ch. 43 - Prob. 1TYKCh. 43 - Prob. 2TYKCh. 43 - Prob. 3TYKCh. 43 - The process of clonal selection accounts for a....Ch. 43 - Prob. 5TYKCh. 43 - Which of the following destroys a target cell by...Ch. 43 - Prob. 7TYKCh. 43 - Prob. 8TYKCh. 43 - Prob. 9TYKCh. 43 - Prob. 10TYKCh. 43 - Prob. 11TYKCh. 43 - Prob. 12TYKCh. 43 - Prob. 13TYKCh. 43 - Prob. 14TYKCh. 43 - Prob. 15TYKCh. 43 - Prob. 16TYKCh. 43 - Prob. 17TYKCh. 43 - What is the key advantage to the use of monoclonal...Ch. 43 - Prob. 19TYKCh. 43 - Prob. 20TYKCh. 43 - Prob. 21TYKCh. 43 - From which of the following conditions would an...
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- Which of the following statements are true for antigen presentation. a. Antigen presentation means that other cells attach the pathogen first and present it to T cells. b. Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells c. Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface. d. Antigen-presenting cells are phagocytic cells e. Antigen presentation is required for T cell activation f. Cytokines released by macrophages are required for T cell activation g. T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells. h. Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activationarrow_forwardWhich of the following is part of the second line of defense against pathogens?a. skin b. mucus membranesc. lysozyme in tears d. phagocytes Which of the following does NOT have MHC class II molecules on the surface of their cell membranes? a. Macrophages.b. Dendritic cells.c. B cells.d. Helper T cells.arrow_forwardAdaptive immunity includes both humoral and cell-mediated immune responses, which interact but also have distinct roles in adaptive immunity. Identify the example of a strictly cell-mediated immune response. A. A cytotoxic T cell destroys an infected host cell. B. A helper T cell activates a B cell. C. A B cell gives rise to plasma cells, which release antibodies. D. An antigen is taken in by an antigen-presenting cell.arrow_forward
- CHAPTER 20 The Lymphatic System and Immunity Matching SECTION 3 Revie w Match each lettered term with the most closely related description. a. opsonization 1 b. helper T cells Two parallel pairs of polypeptide chains Found on helper T cells C. antibody d. class II MHC 3 Active and passive 4 Transfer of antibodies e. costimulation Attacked by HIV f. IgM 6 Enhances phagocytosis g. class I MHC h. IgG 7 MHC proteins present in the plasma membranes of all nucleated cells i. passive immunity j. anaphylaxis 8 Differentiate into memory and plasma cells 9 MHC proteins present in the plasma membranes of all APCS and lymphocytes 9 k. CD4 markers 10 I. acquired immunity 10 Antibodies used to determine blood type 11 m. B lymphocytes 11 Secondary binding process required for T cell activation 12 12 Accounts for 80 percent of all immunoglobulins 13 13 Circulating allergen stimulates mast cells throughout body Match each lettered term with thearrow_forwardAntibodies can have multiple mechanisms of action. The main mechanism is "flagging" a foreign body for phagocytosis and degradation. Another mechanism is... Select one: a. Binding of the Fc domain to T cells for cooperative antigen recognition and destruction. b. Altering the local pH by the formation of carbamate upon reaction with CO2 to denature protein antigens. c. Binding of the variable region to multiple different/distinct sites on the antigen. d. None of these. e. Binding of the antigen in regions essential for its function.arrow_forwardExplain why each choice (a-d) is correct or incorrect. In order for an antigen to activate or sensitize a T helper cell, the antigen must be a. coated with antibodies b. displayed on the surface of an APC along with MHC antigens c. displayed on the surface of another T cell with IgD antibodies d. partly digested by a natural killer cellarrow_forward
- Which of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.arrow_forwardExplain why each choice (a-d) is correct or incorrect. B lymphocytes are categorized as part of the adaptive branch of the immune system for all of the following reasons but one. Which of the following is NOT one of the reasons B lymphocytes are considered part of the adaptive immunity? a.They produce memory cells when activated. b.Their receptors will bind to only one antigen. c.They require co-stimulation from an activated T helper cell d. They are a first line of defense that can begin killing pathogens immediatelyarrow_forwardWhich of the following is not a function of antibodies? Select one: a. They neutralize pathogens by masking the pathogen surface. b. They act as molecular adaptors that bridge together pathogen and phagocyte surfaces. c. They exert toxic effects directly. d. They act as opsonins that mediate phagocytosis. e. They activate complement fixation.arrow_forward
- A patient has contracted an upper respiratory infection caused by a virus. Her initial adaptive immune response to the virus is due to what mechanism of immune surveillance?a. The display of viral antigens by naïve B-cells on class I MHC, which is then recognized by helper T-cells that then activate cytotoxic T-cells.b. The display of viral antigens on class I MHC, which is then displayed to sensitized naïve B-cells, leading to the production of antibodies.c. The display of viral antigens on class II MHC by a sensitized naïve B-cell, which is then activated by a helper T-cell primed to the same antigen to begin producing antibodies.d. The display of viral antigens on class I MHC, which is then displayed to helper T-cells, leading to the activation of naïve cytotoxic T-cells.arrow_forwardTo become a fully activated, antibody-secreting cell, B cells usually need: a. to encounter an antigen or receive a signal delivered by a helper T cell. b. to ingest a foreign invader such as a microobe. c. activation by a plasma cell d. contact with an antigen and helper T cell cytokinesarrow_forwardWhich of the following statements regarding CD4 is incorrect? a. MHC class II molecules present antigens to CD4 T cells. b. CD4 is the receptor used for HIV entry into CD4 T cells. c. CD4 is made up of two separate membrane-bound chains. d. Late in the progression of an HIV infection, the number of CD4 T cells in the circulation diminishes. e. CD4 is referred to as a T-cell co-receptor.arrow_forward
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