The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene. Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

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Answer 1

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Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

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Students have asked these similar questions

The ability to selectively modify the genome in the mouse has revolutionized mouse genetics. Outline the procedure for generating a knockout mouse at a specific genetic locus. How can the loxP-Cre system be used to conditionally knock out a gene? What is an important medical application of knockout mice?

One concern about using genetically-modified organisms is that many of the methods used to create them introduce into the genome DNA from a different species (i.e. foreign DNA). Which of the following methods has the lowest potential of introducing foreign DNA into the genome?A. A gene knockout in mouse using homologous recombination in ES cellsB. Introduction of a P element vector into the Drosophila germ-lineC. Deletion mutations introduced by CRISPR/Cas9D. Microinjection of a transgene into a mouse pronucleus

In contrast with the genomic manipulations of animals and plants described in this chapter, human genetherapy is directed specifically at altering the genomes of somatic cells rather than germ-line cells.Why couldn’t or wouldn’t medical scientists try to alter the genome of human germ-line cells?

Answer 2

Question

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

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Answer 3

Question

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

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Answer 4

Question

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

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Answer 5

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

Answer 6

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Answer 7

Chapter 20, Problem 24PDQ

Summary Introduction

To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.

Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.

Answer 8

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

Answer 9

Summary Introduction

To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.

Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

Answer 10

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Answer 13

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Solution Summary: The author explains the technique of inserting foreign DNA into a host organism’s genome.

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