Although several different mammalian species have been cloned, the efficiency of this process is extremely low. Often tens or even hundreds of oocytes must be implanted with donor nuclei to obtain one healthy live birth. Many researchers believe the difficulties with cloning reside in the epigenetic modifications, such as DNA and histone methylation, that occur within various cells during an individual’s life. How do you suspect such modifications might affect the success of an experiment

Q: One can synthesize RNA from any gene in a test tube (in vitro). You want to synthesize mRNA from a…

A: Translation is a heterocatalytic action of DNA by means of which RNA is synthesize from specific DNA…

Q: You are studying a human gene, and try to express the protein in E. coli bacterial cells. To do…

A: Cloning is the process of creating a genetically identical copy of a biological entity. Cloning can…

Q: Early in development, most human cells turn off expression of an essential component of telomerase,…

A: Telomeres are complex nucleoprotein structures present in the tips of the chromosomes which protects…

Q: Mammals are anatomically and physiologically more complex than roundworms, yet both organisms have…

A: Pleiotropy is defined as the process where a single gene controls or influences the expression of…

Q: If you were to design an epigenetic experiment, how would you design one? Keep in mind a good…

A: Epigenetics is the gene-level alterations that affect the functioning of DNA without actually…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: Genome editing:It is also known as gene editing or genome engineering. It is a type of genetic…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: The introduction of genes into plants is a common practice that has generated not only a host of…

A: No, the tumor-inducing genes are removed from the plasmid, eliminating the threat of tumor…

Q: In the treatment of cancer, the basis for many types of chemotherapyand radiation therapy is that…

A: The tumor is irregular growth of tissue. It is the first stage of tumor development. The…

Q: om college and started working at a biotech startup called Scrofa first job assignment is to clone…

A: Prolactin is defined as a hormone by the pituitary gland at the bottom of the brain. Prolactin…

Q: In a clinical context, doctors are evaluating a therapy for a new patient (say patient B) that they…

A: In the setting of assessing treatment for a modern patient (patient B) who may develop comparable…

Q: You are an expert in DNA-repair mechanisms. You receive a sample of a human cell line derived from…

A: In normal conditions, the cells are capable of fixing the damages caused to DNA before problems…

Q: In yeast, you have sequenced a piece of wild-type DNA and it clearly contains a gene, but you do not…

A: To find the mutated genes one must code all the amino acid of the genetic modified yeast and normal…

Q: magine you are working in a lab that is developing a novelty rose that smells like a stinkhorn…

A: Introduction Recombinant DNA technology is advanced technology to produce hybrids plants and animals…

Q: In this module, you have learned about the use of balancer chromosomes (such as TM2 and TM6C in the…

A: Lethal genes are alleles that result in an end of the entity that possesses them. In basic terms,…

Q: out transformation requires from 105 to 124 genes, collectively termed the com regulon. The com…

A: Transformation is a process in which the DNA is transformed or changed by taking up the DNA that is…

Q: Although a large number of mutagenic chemicals are known,none is known that induces mutations in…

A: Mutation is the process of abrupt changes in the nucleotide sequence or gene in the DNA. Mutation…

Q: Gerald Rubin and Allan Spradling devised a method of introducinga transposon into Drosophila. This…

A: Plasmids are the genetic structures, which can replicate independent of chromosomes. They are the…

Q: The ability to selectively modify the genome in the mouse has revolutionized mouse genetics. Outline…

A: Molecular biology's applications include the development of new protein products, illness prevention…

Q: Retinoblastoma is an extremely rare cancer of the retina in the eye. The disease mainly affects…

A: The investigation into retinoblastoma, a uncommon eye cancer fundamentally influencing children,…

Q: I am a Physician Scientist and have a patient that presents with colorectal cancer. I decide to…

A: Given the scenario you've described, where a novel SNP leads to a premature stop codon in a gene…

Q: From gene expression studies on cancer, you discovered a hypothetical gene called ABCG2 that is…

A: Transgenic approach has been proved to be very useful in studying physiological function of a…

Q: A researcher studying epigenetic changes induced by exercise had participants pedal a stationary…

A: Introduction DNA is the molecular structure that is composed of a pair of polynucleotide chains and…

Q: Briefly answer the question: Exome sequencing to identify a mutation that could cause a particular…

A: Primary findings are the testing results which are obtained and provide required information about…

Q: After decades of work, Dr. Ricky M. isolated a small amount of attractase—an enzyme that produces a…

A: A gene is the essential physical and functional unit of heredity. Genes are comprised of DNA. A…

Q: Itransferases and analyze the cells after they at do you expect to find in the promoter of gene X?…

A: Hematopoietic stem cells (HSCs) resides within the bone marrow, which serves as niche for the…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: Cloning of a eukaryotic gene can be carried out in Escherichia coli. However, for the protein…

A: Introduction Eukaryotes are organisms having well-defined cellular organelles that are specified to…

Q: A certain compound that is an analog of the base cytosinecan become incorporated into DNA. It…

A: The genome is made up of one to several long DNA molecules, and mutations on these molecules can…

Q: Treatment of adenosine deaminase (ADA) deficiency is an exampleof ex vivo gene therapy. Why is this…

A: Gene therapy is a collection of methods that allows correction of a gene defect that has been…

Q: You are working with a fly hair cell developmental system. This Notch/Delta-regulated system results…

A: In this scenario, a forward genetic screen is conducted in a fly hair cell developmental system to…

Q: What is the relationship between methylation and genomic imprinting? O Differential methylation of…

A: The DNA methylation is the process by which the gene expression is turned off. That means the…

Q: By whole-exome sequencing, you have identified an early termination mutation in KLHL4 in a human…

A: "Hi, since you have posted more than one question, we will be answering the first two for you.…

Q: Woolly mammoths have been extinct for about 4,000 years, but we often find their well-preserved…

A: Somatic cell nuclear transfer (SCNT) is a technique in which the viable embryo is developed from egg…

Q: yeast cells, telomerase remains active and maintains telomeres of about 300 base pairs. Propose what…

A: The end areas of chromosomes are called telomeres , are repetitive sequence that protect gene from…

Q: The restriction digests of the cloned Drosophila gene can provide direct visible evidence of a…

A: We can use the technique of Southern blotting to detect and isolate the DNA fragment with the Gene…

Q: DNA repair systems are responsible for maintaining genomic fidelity in normal cells despite the high…

A: Living organisms are constantly exposed to a variety of DNA-damaging substances that can have an…

Q: You are studying celiacs disease and have identified a potential gene for the disease using linkage…

A: Genetics is the study of the heredity, expression of genes and control of phenotypes. There are…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.