Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 2, Problem 23CONQ
In people with maple syrup urine disease, the body is unable to
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In people with maple syrup urine disease, the body is unable tometabolize the amino acids leucine, isoleucine, and valine. One ofthe symptoms is that the urine smells like maple syrup. An unaffected couple produced six children in the following order: unaffecteddaughter, affected daughter, unaffected son, unaffected son, affectedson, and unaffected son. The youngest unaffected son and an unaffected woman have three children in the following order: affecteddaughter, unaffected daughter, and unaffected son. Draw a pedigreethat describes this family. What type of inheritance (dominant orrecessive) would you propose to explain maple syrup urine disease?
A man with thalassemia minor marries a normal woman. What phenotypic ratios of thalassemia-affected children might these parents expect?
Hemophilia is a sex-linked recessive trait. A male hemophiliac and phenotypically normal female have a son with hemophilia.
They would like to have one more child. What is the probability of having a child without hemophilia? Explain using a Punnett square.
Is it possible for a girl to be born with hemophilia? Explain.
Chapter 2 Solutions
Genetics: Analysis and Principles
Ch. 2.1 - 1. Experimental advantages of using pea plants...Ch. 2.1 - The term cross refers to an experiment in which a....Ch. 2.1 - 3. To avoid self-fertilization in his pea plants,...Ch. 2.2 - Prob. 1COMQCh. 2.2 - Prob. 2COMQCh. 2.3 - A pea plant has the genotype rrYy. How many...Ch. 2.3 - A cross is made between a pea plant that is RrYy...Ch. 2.3 - Prob. 3COMQCh. 2.4 - Which of the following would not be observed in a...Ch. 2.4 - Prob. 2COMQ
Ch. 2.5 - A cross is made between AABbCcDd and AaBbccdd...Ch. 2.5 - Prob. 2COMQCh. 2.5 - Prob. 3COMQCh. 2 - 1. Why did Mendel’s work refute the idea of...Ch. 2 - 2. What is the difference between...Ch. 2 - 3. Describe the difference between genotype and...Ch. 2 - 4. With regard to genotypes, what is a...Ch. 2 - 5. How can you determine whether an organism is...Ch. 2 - In your own words, describe Mendels law of...Ch. 2 - Based on genes in pea plants that we have...Ch. 2 - Prob. 8CONQCh. 2 - Do you know the genotype of an individual with a...Ch. 2 - 10. A cross is made between a pea plant that has...Ch. 2 - Prob. 11CONQCh. 2 - 12. Describe the significance of nonparentals with...Ch. 2 - For the following pedigrees, describe what you...Ch. 2 - Ectrodactyly, also known as lobster claw syndrome,...Ch. 2 - Identical twins are produced from the same sperm...Ch. 2 - In cocker spaniels, solid coat color is dominant...Ch. 2 - A cross was made between a white male dog and two...Ch. 2 - 18. In humans, the allele for brown eye color (B)...Ch. 2 - Albinism, a condition characterized by a partial...Ch. 2 - A true-breeding tall plant was crossed to a dwarf...Ch. 2 - 21. For pea plants with the following genotypes,...Ch. 2 - 22. An individual has the genotypeand makes an...Ch. 2 - 23. In people with maple syrup urine disease, the...Ch. 2 - Prob. 24CONQCh. 2 - 25. A true-breeding pea plant with round and Page...Ch. 2 - Prob. 26CONQCh. 2 - 27. What are the expected phenotypic ratios from...Ch. 2 - Prob. 28CONQCh. 2 - Prob. 29CONQCh. 2 - A pea plant that is dwarf with green, wrinkled...Ch. 2 - 31. A true-breeding plant with round and green...Ch. 2 - Wooly hair is a rare dominant trait found in...Ch. 2 - Huntington disease is a rare dominant trait that...Ch. 2 - 34. A woman with achondroplasia (a dominant form...Ch. 2 - 1. Describe three advantages of using pea plants...Ch. 2 - Explain the technical differences between a...Ch. 2 - 3. How long did it take Mendel to complete the...Ch. 2 - 4. For all seven characters described in the data...Ch. 2 - From the point of view of crosses and data...Ch. 2 - 6. As in many animals, albino coat color is a...Ch. 2 - 7. The fungus Melampsora lini causes a disease...Ch. 2 - For Mendels data for the experiment in Figure 2.8,...Ch. 2 - 9. Would it be possible to deduce the law of...Ch. 2 - In fruit flies, curved wings are recessive to...Ch. 2 - A recessive allele in mice results in an unusally...Ch. 2 - Prob. 12EQCh. 2 - Prob. 13EQCh. 2 - Prob. 14EQCh. 2 - 15. A cross was made between two strains of plants...Ch. 2 - A cross was made between two pea plants, TtAa and...Ch. 2 - Consider this four-factor cross: TtRryyAaTtRRYyaa,...
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- Clara has polydactyly, an autosomal dominant that is 80% penetrant. Clara inherited her polydactyly from her mother, her father had no polydactyly in his family. She has an extra toe on her left foot. Her husband Ralph has no polydactyly in his family. A) What is the chance that Clara will have a child that will inherit polydactyly? B) What is the chance that the child will express polydactyly. You can leave these as un-calculated equations.arrow_forwardIn humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h. This is a sex-linked trait found on the X chromosome. A woman with normal blood clotting has four children: a normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is the genotype for each member of the family?arrow_forwardA WOMAN IS HETEROZYGOUS FOR TWO HARMFUL RECESSIVE ALLELES IN DIFFERENT CHROMOSOMES, ONE FOR PHENYLKETONURIA (PKU) AND THE OTHER FOR CYSTIC FIBROSIS (CF). SHE MARRIES AN UNAFFECTED MAN WHO IS A CARRIER FOR NEITHER DISEASE. IF SHE HAS A DAUGHTER, WHAT IS THE PROBABILITY THAT THE CHILD WILL CARRY NEITHER OF THE RECESSIVE ALLELES? EXACTLY ONE? BOTH?arrow_forward
- Suppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.arrow_forwardSickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete dominance in that the heterozygous genotype displays a mild form of the disease known as sickle cell trait while individuals with the homozygous recessive genotype have a severe form of SCA. A man who has severe sickle cell anemia marries a woman who suffers from a mild trait. What is the probabilitu they will have a child with severe SCA?What is the probability they will have a child with mild SCA? What is the probability they will have a normal child? Show ALL work using punnett squares.arrow_forwardBecause Elsa has received a confirmed diagnosis of beta-thalassemia major, which of the following statements is true about her parents? Only her mother carried the gene that caused her blood disorder. Only her father carried the gene that caused her blood disorder. If her parents have another child naturally, there is a 100% chance that the second child will be diagnosed with beta-thalassemia major. If her parents have another child naturally, there is a 25% chance that the second child will be diagnosed with beta-thalassemia major.arrow_forward
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