Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 2, Problem 13CONQ
For the following pedigrees, describe what you think is the most likely inheritance pattern (dominant versus recessive). Explain your reasoning. Filled (black) symbols indicate affected individuals.
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Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance.
image attached
a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR)(ii) an autosomal dominant allele (AD)(iii) a X-linked recessive allele (XR)(iv) a X-linked dominant allele (XD) b. Provide a set of parents that definitively supports your answers in (a).
What pattern of Mendelian inheritance is represented in this pedigree and explain how you made this determination.(please refer to image attached)
The pedigree shows inheritance of the autosomal recessive trait cystic fibrosis in a family. Family members who are
known to have the disease are represented by black shading.
I
1
2
3
4
II 1
3
4
6
8
7
III
1
2
3
4
5
6
7
Part A: Select the best answer from the boxes below to indicate the likely genotypes of the following individuals, where F
indicates the wild-type (usual) allele and f indicates the cystic fibrosis allele. The first part of their number (I, II or III)
indicates their generation or row, whilst the second part of their number (1-8) indicates the individual within that generation
or row.
|-4
Il-3
Il-8
III-3
Chapter 2 Solutions
Genetics: Analysis and Principles
Ch. 2.1 - 1. Experimental advantages of using pea plants...Ch. 2.1 - The term cross refers to an experiment in which a....Ch. 2.1 - 3. To avoid self-fertilization in his pea plants,...Ch. 2.2 - Prob. 1COMQCh. 2.2 - Prob. 2COMQCh. 2.3 - A pea plant has the genotype rrYy. How many...Ch. 2.3 - A cross is made between a pea plant that is RrYy...Ch. 2.3 - Prob. 3COMQCh. 2.4 - Which of the following would not be observed in a...Ch. 2.4 - Prob. 2COMQ
Ch. 2.5 - A cross is made between AABbCcDd and AaBbccdd...Ch. 2.5 - Prob. 2COMQCh. 2.5 - Prob. 3COMQCh. 2 - 1. Why did Mendel’s work refute the idea of...Ch. 2 - 2. What is the difference between...Ch. 2 - 3. Describe the difference between genotype and...Ch. 2 - 4. With regard to genotypes, what is a...Ch. 2 - 5. How can you determine whether an organism is...Ch. 2 - In your own words, describe Mendels law of...Ch. 2 - Based on genes in pea plants that we have...Ch. 2 - Prob. 8CONQCh. 2 - Do you know the genotype of an individual with a...Ch. 2 - 10. A cross is made between a pea plant that has...Ch. 2 - Prob. 11CONQCh. 2 - 12. Describe the significance of nonparentals with...Ch. 2 - For the following pedigrees, describe what you...Ch. 2 - Ectrodactyly, also known as lobster claw syndrome,...Ch. 2 - Identical twins are produced from the same sperm...Ch. 2 - In cocker spaniels, solid coat color is dominant...Ch. 2 - A cross was made between a white male dog and two...Ch. 2 - 18. In humans, the allele for brown eye color (B)...Ch. 2 - Albinism, a condition characterized by a partial...Ch. 2 - A true-breeding tall plant was crossed to a dwarf...Ch. 2 - 21. For pea plants with the following genotypes,...Ch. 2 - 22. An individual has the genotypeand makes an...Ch. 2 - 23. In people with maple syrup urine disease, the...Ch. 2 - Prob. 24CONQCh. 2 - 25. A true-breeding pea plant with round and Page...Ch. 2 - Prob. 26CONQCh. 2 - 27. What are the expected phenotypic ratios from...Ch. 2 - Prob. 28CONQCh. 2 - Prob. 29CONQCh. 2 - A pea plant that is dwarf with green, wrinkled...Ch. 2 - 31. A true-breeding plant with round and green...Ch. 2 - Wooly hair is a rare dominant trait found in...Ch. 2 - Huntington disease is a rare dominant trait that...Ch. 2 - 34. A woman with achondroplasia (a dominant form...Ch. 2 - 1. Describe three advantages of using pea plants...Ch. 2 - Explain the technical differences between a...Ch. 2 - 3. How long did it take Mendel to complete the...Ch. 2 - 4. For all seven characters described in the data...Ch. 2 - From the point of view of crosses and data...Ch. 2 - 6. As in many animals, albino coat color is a...Ch. 2 - 7. The fungus Melampsora lini causes a disease...Ch. 2 - For Mendels data for the experiment in Figure 2.8,...Ch. 2 - 9. Would it be possible to deduce the law of...Ch. 2 - In fruit flies, curved wings are recessive to...Ch. 2 - A recessive allele in mice results in an unusally...Ch. 2 - Prob. 12EQCh. 2 - Prob. 13EQCh. 2 - Prob. 14EQCh. 2 - 15. A cross was made between two strains of plants...Ch. 2 - A cross was made between two pea plants, TtAa and...Ch. 2 - Consider this four-factor cross: TtRryyAaTtRRYyaa,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis?arrow_forwardPedigree analysis is often used to determine mode of inheritance (dominant or recessive, for example). Be sure to read the "Tips for Pedigree Analysis" in Figure 14.15 in 34. your text. Consider the following pedigree for the trait albinism (lack of skin pigmentation) in three generations of a family. (Solid symbols represent individuals with albinism.) Complete the unlabeled pedigree by indicating the genotypes for all involved. From your knowledge of Mendelian inheritance, answer the questions that follow. a. Is this trait caused by a dominant or recessive allele? What is the evidence for your response?arrow_forwardPhenylketonuria (PKU) is a disorder caused by a recessive allele. Two carrier individuals have progeny. Answer the following questions in order and show solutions whenever relevant. a. Indicate the gene notation.b. Derive the expected genotypic and phenotypic ratios.c. If they have a normal child, what is the probability that he or she will be heterozygous?d. If they have three children, what is the probability of having 2 affected children and one normalchild?arrow_forward
- Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?arrow_forwardThe pedigree below tracks the inheritance of a genetic disorder through a family's generation. Determine the probable inheritance mode for the trait shown in the affected individual (the shaded symbols) by answering the following questions. I II 2 3 4 5 7 III 2 3 6 7 8 5 (i) Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your reason. (ii) What TWO (2) other modes of inheritance can be definitely excluded? Explain your answer. Of the remaining modes of inheritance, which is the most likely? Which is less likely? Explain your answers. (ii)arrow_forwardUsing the pedigree, assume that the disease is caused by an autosomal dominant allele, R. Give the genotype of the following individuals: (a) III-4 (the girl at lower right) (b) II-3 (the girl’s mother) (c) II-4 (the girl’s father)arrow_forward
- The pedigree below shows a family with a history of an autosomal recessive genetic disease with one individual's genotype indicated (G denotes the normal allele and g denotes the disease-causing allele). * O 0 O 1/8 1/4 O 1/16 Individual 1's father is known to be heterozygous (*) and his mother is known to be homozygous dominant. Other individuals in the pedigree may be carriers, but are not marked. The question mark (?) indicates that you do not yet know anything about this individual's phenotype with regard to the disease. Part 1 What is the probability that individuals 1 and 2 will have a child (5) who is a male with the disease (the child is unborn and the sex is not yet known)? O 1/4 1 O 1/6 5 1/8 2 01/12 gg 3 Part 2 What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the disease? 6arrow_forwardThe following pedigree describes the inheritance of Lesch-Nyhan syndrome, an x-linked recessive disease. Affected individuals are shaded. what is the probability, that the indicated child (IV.1) will be affected by Lesch-Nyhan syndrome? show solutionarrow_forwardCystic fibrosis is an autosomal recessive disorder that runs in Ann's family. Consider the figure of a pedigree of the known occurrences of cystic fibrosis in her family. Ann Filled (red) circles represent affected females. Filled (red) squares represent affected males. Unfilled (tan) circles, such as Ann's circle, represent symptomless females. Unfilled (tan) squares represent symptomless males.arrow_forward
- A couple who are about to get married learn from studying their family histories that, in both their families, theirunaffected grandparents had siblings with cystic fibrosis(a rare autosomal recessive disease).a. If the couple marries and has a child, what is theprobability that the child will have cystic fibrosis?b. If they have four children, what is the chance that thechildren will have the precise Mendelian ratio of 3:1 fornormal:cystic fibrosis?c. If their first child has cystic fibrosis, what is theprobability that their next three children will be normal?arrow_forwardHelp me create a pedigree of this information: Pedigree analysis: Generation 1: Normal parents (AA x AA) Generation 2: Carrier parents (AA x AS) Generation 3: Affected child (AS x AS) Generation 4: Affected grandchild (SS) This pedigree has two normal parents in the first generation. Second generation carriers carry the sickle cell trait from one parent. The disease is 25% more likely to be inherited in the third generation if both parents have the 'S' allele. If both parents have the 'S' allele, their children will have sickle cell anemia in the fourth generationarrow_forwardRefer to the pedigree below for this question. Individuals who are shaded have a rare autosomal recessive disorder. Those who are not shaded have the dominant phenotype. Let "A' and "a" represent the dominant and recessive alleles, respectively. Fill in the probability functions below to indicate the genotype or probability function for the genotype of each individual. Give all probabilities as fractions that are simplified to the lowest value. Type your fractions in ## format without spaces. For example, one-half should be typed as 1/2. Place a zero in each space that does not have a number. Failure to follow these instructions will result in your answer being marked as incorrect. Note that two of the individuals have been completed for you as examples. Individual 1-3 is genotype O AA + 1 Aa +0 aa Individual II-4 is genotype 1/3 AA + 2/3 Aa + 0 aa Individual 1-6 is genotype AA + Aa + aa Individual II-1 is genotype Aa + AA + aa Individual II-5 is genotype AA + Aa + aa Individual II-7…arrow_forward
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