Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 18, Problem 14TYK
Summary Introduction
Introduction: The non-protein coding RNA (ncRNA) includes a family of small RNAs that are not involved in protein synthesis but play a crucial role in gene regulation. Gene regulation is a vital process that is necessary to produce only specific amounts of required products. The micro RNA (miRNA) belongs to a family of non-coding RNA that regulates gene expression by blocking translation.
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Are the following statements TRUE or FALSE?a. Post-transcriptional RNA processing occurs in the cytoplasm of the cell.b. A primary RNA transcript is often much longer than the mature mRNA that leaves the nucleus.c. Both ends of a pre-mRNA are modified to facilitate RNA splicing.
If an MRNA is alternatively spliced, then
different introns are removed from a pre-MRNA, producing transcripts that will potentially encode proteins with different primary structures.
I.
the MRNA is found in a bacterial cell.
II.
transcription and translation of the MRNA will occur simultaneously.
the alternative splicing happened in the cytoplasm.
IV.
Ay different exons from a pre-mRNA will be spliced together.
V.
the different MRNAS will all have poly-A tails.
VI.
Which of the following is NOT true of miRNAs?
A.
Pri-miRNAs are processed by Drosha in the nucleus to form pre-miRNAs which are cleaved by dicer in the cytoplasm to generate a miRNA.
B.
miRNAs always lead to the degradation of their mRNA targets.
C.
miRNAs can be encoded within the vertebrate genome within introns and within intergenic regions.
D.
miRNAs can generally target more than one mRNA
Chapter 18 Solutions
Study Guide for Campbell Biology
Ch. 18 - In the following diagram of the lac operon, an...Ch. 18 - a. Repressible enzymes usually function in _____...Ch. 18 - a. Give an example of highly methylated and...Ch. 18 - Label the components of the following diagram that...Ch. 18 - a. How is the process of alternate RNA splicing...Ch. 18 - a. Describe how miRNAs regulate gene expression....Ch. 18 - a. What is the difference between determination...Ch. 18 - What type of evidence established that Bicoid...Ch. 18 - a. List three genetic changes that can convert a...Ch. 18 - Complete the following concept map to help you...
Ch. 18 - Fill in the following table to help you organize...Ch. 18 - Prob. 3SYKCh. 18 - Prob. 1TYKCh. 18 - Prob. 2TYKCh. 18 - Prob. 3TYKCh. 18 - Prob. 4TYKCh. 18 - Prob. 5TYKCh. 18 - DNA methylation of cytosine bases a. initiates the...Ch. 18 - Which of the following is not true of enhancers?...Ch. 18 - Prob. 8TYKCh. 18 - A eukaryotic gene typically has all of the...Ch. 18 - Prob. 10TYKCh. 18 - Prob. 11TYKCh. 18 - Which of the following statements explains why a...Ch. 18 - Prob. 13TYKCh. 18 - Prob. 14TYKCh. 18 - Prob. 15TYKCh. 18 - Prob. 16TYKCh. 18 - What would be the fate of a Drosophila larva that...Ch. 18 - Prob. 18TYKCh. 18 - Prob. 19TYKCh. 18 - Prob. 20TYKCh. 18 - Prob. 21TYKCh. 18 - Prob. 22TYKCh. 18 - Prob. 23TYKCh. 18 - Which of the following would most likely account...
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- Differential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single genearrow_forwardAccording to the adaptor hypothesis, is each the following statementstrue or false?A. The sequence of an anticodon in a tRNA directly recognizes acodon sequence in mRNA, with some allowance for wobble.B. The amino acid attached to the tRNA directly recognizes acodon sequence in mRNA.C. The amino acid attached to the tRNA affects the binding of thetRNA to a codon sequence in mRNA.arrow_forwardFor each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosomearrow_forward
- Below is a graphical representation of eukaryotic precursor mRNA. A. Outline each modification that must happen to get a mature m-RNA. B. How does the absence of introns in prokaryotic genes affect prokaryotic gene expression? C. How will gene expression be affected if all of the spliceosomes are removed from the bacteria sample? Explain.arrow_forwardWhich of the following statements about pre-mRNA splicing is FALSE? a. Splicing of an intron requires consensus sequences at the splice donor, the splice acceptor and the branch point of the intron. b. The spliceosome contains proteins and RNA molecules. c. Some snRNAs base pair with splice consensus sequences on the primary transcript. d. Splicing happens before the export of the mRNA to the cytoplasm. e. Splicing happens in the cytoplasm, when spliceosomes move down the pre-mRNA in front of ribosomes.arrow_forwardWhat is the mechanism by which an RNA transcript can be used to silence expression of the same gene? a. What is the name of this mechanism? b. Briefly describe the steps of the process and the two possible fates for the silenced RNA transcript? c. Predict how a transversion in the miRNA sequence would affect this process.arrow_forward
- For each of the following, identify the type of RNA involved (mRNA, rRNA, or tRNA). a. Transports the correct amino acid to the ribosome, using the information encoded in the mRNA. b. Is a major component of ribosomes. c. Specifies the order of amino acids in a protein, using a series of three-base codons, where different amino acids are specified by particular codons. d. Contains a three-base anticodon that pairs with a complementary codon revealed in the mRNA. e. Assists in making the bonds that link amino acids together to make a protein.arrow_forwardMatch each of the following descriptions to the type of regulatory RNA affecting a "target" gene (aka, the gene the regulatory RNA is regulating). Use each answer once. This regulatory RNA may increase siRNA transcription of the target gene by recruiting activator proteins. secondary structures on RNA can become... IncRNA these regulatory RNAs regulate gene miRNA expression post transcriptionally generally by binding to the 3'-UTR regions of their target RNAs > >arrow_forwardYou are studying how gene expression is regulated in the cell. For gene z, you find that while there are high levels of mRNA in the cell, there are low levels of the protein encoded by gene z. Describe a regulatory mechanism that could explain this finding that occurs after translation.arrow_forward
- Which of the following statements are true about eukaryotic mRNA?a. The sigma factor is essential for the correct initiationof transcription.b. Processing of the nascent mRNA may begin beforeits transcription is complete.c. Processing takes place in the cytoplasm.d. Termination is accomplished by the use of a hairpinloop or the use of the rho factor.e. Many RNAs can be transcribed simultaneously fromone DNA templatearrow_forwardWhy might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardA geneticist induces a mutation in eukaryote cells. The mutation results in an inability to form the poly(A) tail during processing of pre-mRNA. What does this mean for the mature mRNA and what will be the effect on these cells? Possible Answers: A. The mRNA will be spliced, but will not have a 5' cap. B. The mRNA will likely be degraded. C. The mRNA will not be cleaved. D. The mRNA will have too many Gs and Cs.arrow_forward
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