Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Textbook Question
Chapter 18, Problem 9IQ
- a. List three genetic changes that can convert a proto-oncogene into an oncogene.
- b. List three possible functions of tumor-suppressor proteins.
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Tissues and differentiation:
a) Explain what is meant by determination and differentiation
b) Explain the difference between an oncogene and a tumor suppressor gene and describe how they are involved in the development of cancer
D. What is the best term for a normal INK gene? (tumor suppressor) (inactive tumor suppressor) (oncogene)
(proto-oncogene) (oncogene or tumor suppressor) (beats me).
E. Suppose you have cells that have permanently active ink protein as in C. The cells also have permanently active
E2F or permanently active ras. (Consult texts or handouts for roles of E2F and ras.)
E-1. If your cells have active E2F and active ink, then your cells should (grow normally) (fail to grow)
grow uncontrollably) (can't predict).
E-2. If your cells have active ras and active ink, then your cells should (grow normally) (fail to grow)
grow uncontrollably) (can't predict).
Define the following terms: tumor, neoplasia, anaplasia, metastasis, proto-oncogene, oncogene, and tumor suppressor gene.
Chapter 18 Solutions
Study Guide for Campbell Biology
Ch. 18 - In the following diagram of the lac operon, an...Ch. 18 - a. Repressible enzymes usually function in _____...Ch. 18 - a. Give an example of highly methylated and...Ch. 18 - Label the components of the following diagram that...Ch. 18 - a. How is the process of alternate RNA splicing...Ch. 18 - a. Describe how miRNAs regulate gene expression....Ch. 18 - a. What is the difference between determination...Ch. 18 - What type of evidence established that Bicoid...Ch. 18 - a. List three genetic changes that can convert a...Ch. 18 - Complete the following concept map to help you...
Ch. 18 - Fill in the following table to help you organize...Ch. 18 - Prob. 3SYKCh. 18 - Prob. 1TYKCh. 18 - Prob. 2TYKCh. 18 - Prob. 3TYKCh. 18 - Prob. 4TYKCh. 18 - Prob. 5TYKCh. 18 - DNA methylation of cytosine bases a. initiates the...Ch. 18 - Which of the following is not true of enhancers?...Ch. 18 - Prob. 8TYKCh. 18 - A eukaryotic gene typically has all of the...Ch. 18 - Prob. 10TYKCh. 18 - Prob. 11TYKCh. 18 - Which of the following statements explains why a...Ch. 18 - Prob. 13TYKCh. 18 - Prob. 14TYKCh. 18 - Prob. 15TYKCh. 18 - Prob. 16TYKCh. 18 - What would be the fate of a Drosophila larva that...Ch. 18 - Prob. 18TYKCh. 18 - Prob. 19TYKCh. 18 - Prob. 20TYKCh. 18 - Prob. 21TYKCh. 18 - Prob. 22TYKCh. 18 - Prob. 23TYKCh. 18 - Which of the following would most likely account...
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- Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain the difference between an oncogenic and a tumour suppressor gene and describe how they are involved in the onset of cancerarrow_forwardDescribe the genetic changes that convert proto-oncogenesinto oncogenes or inactivate tumor-suppressor genes.arrow_forwardList and define the two general types of tumor.arrow_forward
- Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.arrow_forwardExplain the normal regulation of proto-oncogenes and tumor suppressor genes that prevents cells from becoming cancerous.arrow_forwardDescribe the key characteristics of cancer.arrow_forward
- EXPLAIN BRIEFLY: Explain the molecular mechanisms of cancers caused by a P53 gene mutation.arrow_forwardA. What are the 4 key signalling cues communicated within a cell to regulate cellular behaviour. B. How are these signalling cues abnormal in cancerous cells?arrow_forwardDescribe the difference between a tumor suppressor and an oncogene with respect to the actual causes of cancer.arrow_forward
- Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the organismal level.arrow_forwardPlease discuss the difference between cancers caused by tumor viruses and cancers caused by oncogenes. Does the etiology of a cancer influence its manifestation?arrow_forward-Describe the seven hallmarks of cancer i) List the seven hallmarks ii) Connect each hallmark to the type of change -Explain importance of p53 i) Know the function of p53 ii) Explain how loss of p53 can result in several hallmarks of cancerarrow_forward
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