Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 18, Problem 1TYK
Summary Introduction
Introduction: Gene regulation is the process of controlling gene expression. The gene regulation process involves different mechanisms to produce gene products. The negative gene regulation process inhibits the expression of a gene, while the positive gene regulation process promotes the expression of a gene.
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E. coli has five genes that code for enzymes that make tryptophan. These genes
are regulated by a single promoter and transcribed as one long gene. The
presence of tryptophan shut down the production of tryptophan by the cell by
binding to the repressor. This changes the repressors shape allowing it to bind to
DNA operator, blocking RNA polymerase and cutting off the production of
tryptophan. a. Describe what would happen to the operon if some of the cells
had a mutation on the repressor, not allowing it to bind with tryptophan. The
repressor is described as an allosteric protein. What does this mean? b. Does the
tryptophan model demonstrate an inducible or repressible operon? What is your
evidence?*
E. coli has five genes that code for enzymes that make tryptophan. These genes
are regulated by a single promoter and transcribed as one long gene. The
presence of tryptophan shut down the production of tryptophan by the cell by
binding to the repressor. This changes the repressors shape allowing it to bind to
DNA operator, blocking RNA polymerase and cutting off the production of
tryptophan. a. Describe what woud happen to the operon if some of the cells
had a mutation on the repressor, not allowing it to bind with tryptophan. The
repressor is described as an allosteric protein. What does this mean? b. Does the
tryptophan model demonstrate an inducible or repressible operon? What is your
evidence? *
In E. coli, induction in the lac operon and repression in the trp operon are both examples of
a. negative control by a repressor.
b. positive control by a repressor.
c. negative control by an activator.
d. positive control by a repressor.
Chapter 18 Solutions
Study Guide for Campbell Biology
Ch. 18 - In the following diagram of the lac operon, an...Ch. 18 - a. Repressible enzymes usually function in _____...Ch. 18 - a. Give an example of highly methylated and...Ch. 18 - Label the components of the following diagram that...Ch. 18 - a. How is the process of alternate RNA splicing...Ch. 18 - a. Describe how miRNAs regulate gene expression....Ch. 18 - a. What is the difference between determination...Ch. 18 - What type of evidence established that Bicoid...Ch. 18 - a. List three genetic changes that can convert a...Ch. 18 - Complete the following concept map to help you...
Ch. 18 - Fill in the following table to help you organize...Ch. 18 - Prob. 3SYKCh. 18 - Prob. 1TYKCh. 18 - Prob. 2TYKCh. 18 - Prob. 3TYKCh. 18 - Prob. 4TYKCh. 18 - Prob. 5TYKCh. 18 - DNA methylation of cytosine bases a. initiates the...Ch. 18 - Which of the following is not true of enhancers?...Ch. 18 - Prob. 8TYKCh. 18 - A eukaryotic gene typically has all of the...Ch. 18 - Prob. 10TYKCh. 18 - Prob. 11TYKCh. 18 - Which of the following statements explains why a...Ch. 18 - Prob. 13TYKCh. 18 - Prob. 14TYKCh. 18 - Prob. 15TYKCh. 18 - Prob. 16TYKCh. 18 - What would be the fate of a Drosophila larva that...Ch. 18 - Prob. 18TYKCh. 18 - Prob. 19TYKCh. 18 - Prob. 20TYKCh. 18 - Prob. 21TYKCh. 18 - Prob. 22TYKCh. 18 - Prob. 23TYKCh. 18 - Which of the following would most likely account...
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- Compare and contrast the activities of an activator protein anda repressor protein.arrow_forwardThe cI gene that encodes the λ repressor has two promotersdesignated PRE and PRM. Which of the following statements isfalse?a. PRE is activated by the cII protein.b. PRE is activated by the λ repressor.c. PRM is turned on after PRE.d. PRM is needed to maintain the lysogenic cycle.arrow_forwardTranscriptional regulation often involves a regulatory protein that binds to a segment of DNA and a small effector molecule that binds to the regulatory protein. Do each of the following terms apply to a regulatory protein, a segment of DNA, or a small effector molecule? A. Repressor B. Inducer C. Operator site D. Corepressor E. Activator F. Attenuator G. Inhibitorarrow_forward
- What type of control generally involves binding of a repressor protein to a regulatory DNA sequence? (one or two word answer only, please)arrow_forwardTwo different types of gene regulatory elements are DNA sequence and protein-based. Which of the following describes them, respectively? a. one blocks translation, the other blocks transcription b. The first is an aporepressor, the second is a promoter c. The first is an enhancer, the second is a repressor d. The first is a activator, the second is a an attenuator e. one is an activist, the other is a protestorarrow_forwardCompare and contrast regulation by a repressor and an activator.arrow_forward
- Is each of the following statements true or false? A. An enhancer is a type of regulatory element. B. A core promoter is a type of regulatory element. C. Regulatory transcription factors bind to regulatory elements. D. An enhancer may cause the down regulation of transcription.arrow_forward1. (a) Binding of inducer protein to repressor protein Gene is switched ON Gene is switched OFF Does NOT affect the gene expression (b) Repressor protein binding at DNA upstream Gene is switched ON Gene is switched OFF Does NOT affect the gene expression (c) Operator is not bound with the repressor Gene is switched ON Gene is switched OFF Does NOT affect the gene expressionarrow_forwardContrast the role of the repressor in an inducible system and in a repressible system.arrow_forward
- A mutation in the operator region of the trp operon can prevent the trp repressor from binding to this operator. When these mutant cells are placed in a solution containing chicken broth, which of the following happens? a. Tryptophan would bind to the repressor. b. The Repressor would bind to the operator irrespective of the presence of amino acids in the environment. c. The transcription of the trip operon would be inhibited. d. The transcription of the repressor protein is inhibitedarrow_forwardAfter treating cells in tissue culture with an HDAC inhibitor, which of the following is the most likely outcome? A. Repression of transcription B. Promoter methylation C. Enhanced splicing D. Activation of transcription E. Depends on the cell typearrow_forwardWhich of the following best explains how the prokaryotic expression of a metabolic protein can be regulated when the protein is already present at a high concentration? a.Repressor proteins can be activated and bind to regulatory sequences to block transcription. b.Regulatory proteins can be inactivated to increase gene expression. c.Transcription factors can bind to regulatory sequences to increase RNA polymerase binding. d.Histone modification can prevent transcription of the gene.arrow_forward
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