Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15, Problem 2CONQ
Discuss the structure and function of regulatory elements. Where are they located relative to the core promoter?
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Students have asked these similar questions
a) what is a promoter and give the element and their functions of E.coli promoter
b) what are eukaryotic transcription factor and list the class 2 general transcription factors and state their functions
Explain why knowing the orientation of a promoter is critical when determining the amino acid sequence of an encoded protein.
Match each of the following descriptions to the type of regulatory RNA affecting a "target"
gene (aka, the gene the regulatory RNA is regulating). Use each answer once.
This regulatory RNA may increase
siRNA
transcription of the target gene by
recruiting activator proteins.
secondary structures on RNA can
become...
IncRNA
these regulatory RNAs regulate gene
miRNA
expression post transcriptionally
generally by binding to the 3'-UTR
regions of their target RNAs
>
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Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are two differences between promoters and enhancers? (Hint: where are they located relative to the transcription start site?)arrow_forwardBriefly describe the significance of regulatory factors in transcription process. Why the promoter is called an essential regulatory element.arrow_forwardExplain how a transcriptional fusion to a reporter gene, combined with site directed mutagenesis, can indicate key nucleotides in a regulatory region. Name one in vitro technique that can be used to further confirm the significance of these regions.arrow_forward
- Explain how the expression of a single gene can be quickly,efficiently,and specifically shut down at the transcriptional,posttranscriptional,and posttranslational stages through thecoordinated expression of a transcriptional repressor, an miRNA,and a ubiquitin ligase.arrow_forwardAnswer these questions concerning promoters. a) What role do promoters play in transcription? b) What is the common structure of bacterial promoter with respect to consensus sequences? c) Eukaryotic promoters are more variable than bacterial promoters. Why? d) What is the meaning of the term alternative promoter? How does the use of alternative promoters affect transcription?arrow_forwardOutline the essential features of the three basic phases of transcription. How might each of them be targeted to regulate gene expression? Which of the three phases is the most common target of regulatory mechanisms?arrow_forward
- How were bacterial promoters first identified? Discuss their placement within the gene and roles in transcription initiation. Further discuss how the holoenzyme engages a promoter.arrow_forwardDistinguish between the cis-acting regulatory elements referred to as promoters and enhancers.arrow_forwardWhat is meant by the term transcription factor modulation? List three general ways this can occur.arrow_forward
- What is the difference between a promoter and an enhancer?arrow_forwardWhat are general transcription factors? When do you expect to find them? What is a cis acting regulatory sequence? Where are they located in comparison with the gene they are regulating?arrow_forward"Promoter is unmethylated, and gene can be transcribed" Illustrate this diagramtically ?arrow_forward
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