What are general transcription factors? When do you expect to find them? What is a cis acting regulatory sequence? Where are they located in comparison with the gene they are regulating?

How does alternative splicing affect gene expression?

Why is protein N important in the transcription of cII?

What are the histone modifications for transcription?

Using the transcription unit diagrammed below, in which exons are represented by blue boxes and introns are represented by the connecting lines.  You discover a single base deletion in region E of this DNA sequence. Regarding transcription, this mutation will likely: 1.) Result in an alteration to the mRNA sequence. 2.)Have no effect on transcription or the mRNA sequence 3.)Prevent transcription at the TATAA box 4.) Result in an increase or decrease in the amount of mRNA transcribed

What does it mean to study the subcellular localization of a protein? What are two techniques that could be used to study the subcellular localization of a protein? Then specify how each of these techniques could be used to study a transcription factor in liver cells