Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15, Problem 22CONQ
Histones are thought to be displaced as RNA polymerase is transcribing a gene. What would be the potentially harmful consequences if histones were not put back onto a gene after RNA polymerase had passed?
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Histones are thought to be displaced as RNA polymerase is transcribing a gene. What would
the potentially harmful consequences if histone were not put back onto a gene after RNA
polymerase has passed?
During the process of transcription, the polymerase must handle several distinct polynucleotide chains: the double-stranded DNA ahead of the polymerase, the single-stranded template DNA, the nontemplate DNA strand, and the freshly-synthesized mRNA. How does the polymerase keep each of these strands--as well as the incoming ribonucleotides needed for the polymerase reaction--separate?
What is the result when the core histones are acetylated via histone
acetyltransferase?
A) The result depends on which histone is modified.
B) The DNA becomes more tightly associated with the core.
O C) The DNA becomes less associated with the core.
This modification has no effect on how tightly associated DNA will become
with the core.
Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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- RNA polymerase must detect and transcribe discrete genes from within large stretches of DNA. What marks the beginning of the unit to be transcribed?arrow_forwardWhen a gene is being transcribed, the nitrogenous base code must be made available for reading by polymerizing enzymes. Discuss where it begins?arrow_forwardClustered sites where replication of multiple DNA molecules takes place are called transcription factories. a) True b) Falsearrow_forward
- A principle of biology is the genetic material provides ablueprint for reproduction. Explain how gene regulation is animportant mechanism for reproduction and sustaining life.arrow_forwardHow do you think that transcription randomizes positions of nucleosomes and repression restores the ordering after transcription? How might you test to see if there was an exchange of histone subunits during transcription or if the nucleosome is truly transferred as a single unit? Would you expect the DNA band representing the distance from the restriction enzyme site to the hypersensitive site to be a single band or a smear? Defend your answer.arrow_forwardIf a gene sequence is more tightly coiled around histones, then which of the following is the most likely consequence? A) This gene is more likely to undergo mutation as it is being expressed B) This gene is unlikely to be transcribed while in this conformation C) This gene will be transcribed often while in this conformation D) This gene will be translated more efficiently .arrow_forward
- Present an overview of the manner in which chromatin can be remodeled. Describe the manner in which these remodeling processes influence transcription.arrow_forwardA codon is a triplet of bases which codes for an amino acid. Exons are intervening sequence that are not spliced out during transcriptiona modification. RNA can never be double-stranded like DNA in both prokaryotes and eukaryotes. Alteration in BRCA-2 results to breast and ovarian cancer because of defect in the repair by homologous recombination. Write T if the statement is true and write F if the statement is falsearrow_forwardScientists developed a marker technology to examine the function of RNA polymerase in yeast cells. With the markers, they can follow the transcription process as it unfolds. A representation of a DNA strand that scientists were observing is shown in the diagram. At which of the following points does the RNA polymerase begin transcribing the DNA? ABCDarrow_forward
- Describe what would happen to the lac operon in a low-lactose environment and in a high lactose environment. a) How will each of these environments affect gene expression? b) What would happen to the repressor in each case? c) How will each of these environments affect RNA polymerase?arrow_forwardDescribe three (3) ways in which the primary transcript is modified as it is converted to mRNA.arrow_forwardWhich of the following is true about chromodomains? a) bind methylated histone tails b) are associated with repression c) both a and b d) none of the abovearrow_forward
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