Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 4, Problem 25CONQ
Summary Introduction
To review:
The comparisonof the
Introduction:
Change in the shape of RBC(red blood cells) due to change in the beta (β) globin chain of the hemoglobin leads to sickle cell anemia. Sickle cell anemia is an autosomal recessive disorder, which occurs due to mutation at the sixth position of theβ-globin chain. It is also an example of a single base mutationor single
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Explain the differences between an individual homozygous for the sickle hemoglobin allele (HbS/HbS) and one who is heterozygous (HbA/HbS). Consider the hemoglobin molecule, cells, and disease.
The following is a summary of the possible sickle-cell genotypes and phenotypes:
AA - cojmpletely normal
AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin)
SS - sickle-cell anemia (all abnormal hemoglobin)
Fill in the punnett square and answer the question:
If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?
Cross a homozygous tall female carrier for hemophilia with a short normal male. Give genotypic and phenotypic ratios of the offspring. Use T = Tall, and t = short for one trait, and H =normal, and h = hemophilia for the second sex-linked trait. The Cross is: XHXhTT X XYtt Question: What is the Ggenotypic ratio?
a.) None is correct
b.) 3:2:1:4
c.) 4:4:4:4
d.) 1:2:4:4
Chapter 4 Solutions
Genetics: Analysis and Principles
Ch. 4.1 - 1. Which of the following statements is true?
a....Ch. 4.2 - 1. Which of the following is not an example of a...Ch. 4.2 - Prob. 2COMQCh. 4.2 - 3. Polydactyly is a condition in which a person...Ch. 4.3 - The outcome of an individuals traits is controlled...Ch. 4.4 - Prob. 1COMQCh. 4.4 - Prob. 2COMQCh. 4.5 - Prob. 1COMQCh. 4.5 - Hemophilia is a blood-clotting disorder in humans...Ch. 4.6 - Prob. 1COMQ
Ch. 4.7 - 1. The Manx phenotype in cats is caused by a...Ch. 4.8 - Which of the following is a possible explanation...Ch. 4.9 - 1. Two different strains of sweet peas are...Ch. 4.9 - If the F1 offspring from question 1 are allowed to...Ch. 4 - 1. Describe the differences among dominance,...Ch. 4 - Discuss the differences among sex-influenced,...Ch. 4 - 3. What is meant by a gene interaction? How can a...Ch. 4 - Lets suppose a recessive allele encodes a...Ch. 4 - 5. A nectarine is a peach without the fuzz. The...Ch. 4 - 6. An allele in Drosophila produces a star-eye...Ch. 4 - A seed dealer wants to sell four-oclock seeds that...Ch. 4 - 8. The blood serum from one individual (let’s call...Ch. 4 - 9. Which blood type phenotypes (A, B, AB, and/or...Ch. 4 - A woman with type B blood has a child with type O...Ch. 4 - A type A woman is the daughter of a type O father...Ch. 4 - In Shorthorn cattle, coat color is controlled by a...Ch. 4 - In chickens, the Leghorn variety has white...Ch. 4 - Propose the most likely mode of inheritance...Ch. 4 - 15. A human disease known as vitamin D-resistant...Ch. 4 - 16. Hemophilia is an X-linked recessive trait in...Ch. 4 - 17. Incontinentia pigmenti, a rare, X-linked...Ch. 4 - 18. Scurs in cattle is a sex-influenced trait. A...Ch. 4 - In rabbits, the color of body fat is controlled by...Ch. 4 - Prob. 20CONQCh. 4 - 21. The trait of feathering in fowls is a...Ch. 4 - Based on the pedigree shown here for a trait...Ch. 4 - 23. The pedigree shown here involves a trait...Ch. 4 - Lets suppose you have pedigree data from thousands...Ch. 4 - Prob. 25CONQCh. 4 - 26. In humans, a very rare dominant allele that...Ch. 4 - 27. A sex-influenced trait in humans affects the...Ch. 4 - Three coat-color patterns that occur in some...Ch. 4 - Prob. 1EQCh. 4 - 2. In chickens, some varieties have feathered...Ch. 4 - 3. In sheep, the formation of horns is a...Ch. 4 - Prob. 4EQCh. 4 - In the clover butterfly, males are always yellow,...Ch. 4 - The Mic2 gene in humans is present on both the X...Ch. 4 - 7. Duroc Jersey pigs are typically red, but a...Ch. 4 - 8. As shown in Figure 4.17, coat color in rodents...Ch. 4 - 9. Summer squash exist in long, spherical, or disk...Ch. 4 - In a species of plant, two genes control flower...Ch. 4 - 11. Red eyes is the wild-type phenotype in...Ch. 4 - 12. As mentioned in Experimental Question E11, red...Ch. 4 - Lets suppose you were looking through a vial of...Ch. 4 - 14. When examining a human pedigree, what features...Ch. 4 - Lets suppose a gene exists as a functional...Ch. 4 - In oats, the color of the chaff is determined by a...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Cross a homozygous tall female carrier for hemophilia with a short normal male. Give genotypic and phenotypic ratios of the offspring. Use T = Tall, and t = short for one trait, and H =normal, and h = hemophilia for the second sex-linked trait. The Cross is: XHXhTT X XYtt . Question: How many are tall/normal male ?arrow_forwardThe following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin) If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?arrow_forwardCross a homozygous tall female carrier for hemophilia with a short normal male. Give genotypic and phenotypic ratios of the offspring. Use T = Tall, and t = short for one trait, and H =normal, and h = hemophilia for the second sex-linked trait. The Cross is: XHXhTT X XYtt . Question: What is the phenotypic ratio? a. 1:2:4:4 b. 4:4:4:4 c. 3:2:1:4 d. None is correctarrow_forward
- Write the genotype for each person based on : -Homozygous for B allele -Heterozygous for A allele -Type O -Type A and had a type O parent -Type AB -Blood that can be donated to anybody -Can only received blood from a type O donor There is a couple, the blood type of a male is A+ and the female is o+. What are all the possible blood types of their children in the future? Illustrate the inheritance in a Punnett Square showing all the possible blood types from the offspring of the male and female.arrow_forwardThe following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin) Make a punnett square for help answering the question: If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?arrow_forwardBACKGROUND: Sickle cell disease is caused by a change in the gene for hemoglobin, which is the oxygen-carrying protein in red blood cells. Individuals who are homozygous for the sickle cell trait often cannot endure exercise. Individuals who are heterozygous for the trait can have sickle cell attacks under extreme conditions. Normal individuals (genotype: Hbnorm Hbnorm ) have only normal hemoglobin. Homozygous sickle cell individuals (genotype: Hbsc Hbsc ) 'have only sickle cell hemoglobin. Heterozygous individuals (genotype: Hbnorm Hbsc ) have both normal and sickle cell hemoglobin. terry Smith collapsed while running a race for his track team. A doctor said he had a sickle cell attack. Genetic tests were run on several family members. The test results are shown below. An X indicates that form of hemoglobin in red blood cells. PROBLEM: How can you determine the genotypes of people in a family? Subject Normal Hemoglobin Sickle Cell Hemoglobin Jerry Jerry's brother Jerry's younger…arrow_forward
- Describe the phenotype of individuals who inherit one copy of the HbS allele and one copy of the HbA allele-Sickle Cell Trait ( find the source to support the information)arrow_forwardDescribe the phenotype of individuals who inherit two copies of the HbS allele-Sickle Cell Disease. ( find a source to support the information)arrow_forwardConsider the MN blood system in humans. This blood system consists of only two alleles, M and N, and they are codominant to each other. Three genotypes are possible, and these genotypes can be easily identified through simple blood typing procedures, including the heterozygous MN due to the codominant mode of inheritance. Consider the following data: Phenotype Genotype Number of individuals M MM 89 MN MN 162 N NN 79 1. How many alleles exist in this population? 2. What is the genotypic frequency of the M blood type in the population? 3. What is the allelic frequency of M? 4. What is the allelic frequency of N? 5. What is the genotypic frequency of MN? Write your answers directly. You do not need to show your solution.arrow_forward
- List the 6 possible genotypes of the four blood types. Identify the parentalgenotypes that could produce children with blood type AO.arrow_forwardImagine you have a blood group of "X" which is recessive and expressed by xx. The dominant blood groups are Y and Z, where homozygous of these alleles are expressed as YY and ZZ, respectively. What will be the genotype of your parents blood group? Why? Please explain in your own words. [Max 200 words]arrow_forwardWith regard to the ABO blood types in humans, determine the genotype of the male parent and female parent shown here: Male parent: Blood type B; mother type O Female parent: Blood type A; father type B Predict the blood types of the offspring that this couple may have and the expected proportion of each.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning